CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities:
Net loss	$ (20,452)	$ (85,838)	$ (50,363)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		2,223	2,291
Amortization and premium of marketable securities, net		1,366	(3,407)
Loss (gain) on sale or disposal of assets		1	(23)
Intangible asset impairment	3,500		3,500
Gain on fair value remeasurement of contingent consideration	(1,901)	(6,862)	(1,160)
Non-cash income tax benefit	(227)		(227)
Stock-based compensation expense		11,103	5,813
Changes in operating assets and liabilities:
Accounts and other receivables		(17)	1,549
Prepaid and other current assets		(7,928)	(2,261)
Accounts payable and accrued expenses		720	1,757
Other liabilities		3,262	(3,855)
Net cash used in operating activities		(81,970)	(46,386)
Cash flows from investing activities:
Sales and maturities of marketable securities		192,866	129,000
Purchases of marketable securities		(132,613)	(325,342)
Acquisition of property and equipment		(1,593)	(895)
Proceeds from sale or disposal of assets		69	25
Net cash provided by (used in) investing activities		58,729	(197,212)
Cash flows from financing activities:
Net proceeds from stock issuances			269,893
Proceeds from issuance of stock from employee benefit plans		2,681	2,053
Net cash provided by financing activities		2,681	271,946
Net (decrease) increase in cash and cash equivalents		(20,560)	28,348
Cash and cash equivalents at beginning of period		39,143	43,836
Cash and cash equivalents at end of period	$ 72,184	18,583	72,184
Non-cash investing activities
Accrued construction in progress		$ 38	$ 46