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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (59,054) $ (29,911)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,552 1,539
Amortization and premium of marketable securities, net 1,308 (173)
Loss (gain) on sale or disposal of assets 57 (24)
(Gain) loss on fair value remeasurement of contingent consideration (6,862) 741
Stock-based compensation expense 6,607 2,784
Changes in operating assets and liabilities:    
Accounts and other receivables 75 1,306
Prepaid and other current assets (8,485) (1,544)
Accounts payable and accrued expenses (862) (750)
Litigation settlement payable 15,000  
Other liabilities 3,886 (3,982)
Net cash used in operating activities (46,778) (30,014)
Cash flows from investing activities:    
Sales and maturities of marketable securities 106,756 116,000
Purchases of marketable securities (69,847) (85,739)
Acquisition of property and equipment (1,248) (710)
Proceeds from sale or disposal of assets 0 24
Net cash provided by investing activities 35,661 29,575
Cash flows from financing activities:    
Proceeds from issuance of stock from employee benefit plans 375 49
Net cash provided by financing activities 375 49
Net decrease in cash and cash equivalents (10,742) (390)
Cash and cash equivalents at beginning of period 39,143 43,836
Cash and cash equivalents at end of period 28,401 $ 43,446
Non-cash investing activities    
Accrued construction in progress $ 54