For contingent consideration arrangements recognized in connection with a business combination, this element represents an estimate of the high-end of the potential range (undiscounted) of the consideration which may be paid.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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-SubTopic 10
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Collaboration Agreements (Details) - USD ($) $ in Millions	12 Months Ended
Collaboration Agreements (Details) - USD ($) $ in Millions	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Collaborative Agreements
License fee expense	$ 0.1	$ 0.2	$ 0.1
Southampton \| Southampton
Collaborative Agreements
Potential milestone payment	1.0
Amgen \| Amgen
Collaborative Agreements
Potential milestone payment	0.9
Yale \| Yale
Collaborative Agreements
Potential milestone payment	$ 3.0