Income Taxes - Reconciliation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Reconciliation between the amount of reported income tax and the amount computed using U.S. Statutory rate
Pre-tax loss	$ (60,947)	$ (50,878)	$ (151,949)
Loss at statutory rates	(12,799)	(10,684)	(31,909)
Research and development credits	(1,778)	(1,902)	(2,056)
State taxes	(5,802)	(2,170)	(6,406)
Other	(1,152)	(1,011)	(1,175)
Change in fair value remeasurement of contingent consideration	(886)	(272)	(6,220)
Intangible impairment			19,105
Impact of pass-through entities			(913)
Expiration of NOLs and R&D credit	20,294	18,966
Change in Valuation Allowance	956	$ (2,927)	28,809
Income tax (benefit) provision	$ (1,167)		$ (765)