CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018
Cash Flows From Operating Activities:
Net Loss	$ (40,431)	$ (141,781)
Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities:
Depreciation and Amortization	3,713	2,856
Amortization of Intangible Assets	0	224
Amortization and Premium of Marketable Securities, Net	(980)	(666)
Loss on Sale or Disposal of Assets	7	1,170
Goodwill Impairment		90,976
Intangible Asset Impairment		18,677
Other Asset Impairment	1,800
Gain on Fair Value Remeasurement of Contingent Consideration	(1,612)	(27,968)
Non-Cash Income Tax Benefit		(765)
Stock-Based Compensation Expense	3,864	6,329
Changes in Operating Assets and Liabilities:
Accounts and Other Receivables	2,435	(790)
Prepaid and Other Current Assets	208	1,545
Accounts Payable and Accrued Expenses	(884)	(9,246)
Other Liabilities	(3,535)	(366)
Net Cash Used in Operating Activities	(35,415)	(59,805)
Cash Flows From Investing Activities:
Sales and Maturities of Marketable Securities	91,473	178,335
Purchases of Marketable Securities	(77,011)	(151,558)
Acquisition of Property and Equipment	(626)	(651)
Proceeds from Sale or Disposal of Assets	20	342
Net Cash Provided by Investing Activities	13,856	26,468
Cash Flows From Financing Activities:
Net Proceeds from Stock Issuances	13,826	25,453
Proceeds from Issuance of Stock from Employee Benefit Plans	9	419
Net Cash Provided by Financing Activities	13,835	25,872
Net Decrease in Cash and Cash Equivalents	(7,724)	(7,465)
Cash and Cash Equivalents at Beginning of Period	24,310	40,288
Cash and Cash Equivalents at End of Period	$ 16,586	32,823
Non-cash Investing Activities
Accrued construction in progress		86
Non-cash Supplemental Disclosure
Shares issued to former Kolltan executive for settlement of severance		$ 65