CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
REVENUES:
Total Revenues	$ 546	$ 941	$ 2,686	$ 7,774
OPERATING EXPENSES:
Research and Development	11,101	11,918	32,333	55,242
General and Administrative	3,403	3,722	12,207	14,936
Goodwill Impairment				90,976
Intangible Asset Impairment				18,677
Other Asset Impairment			1,800
Gain on Fair Value Remeasurement of Contingent Consideration	(2,114)	(6,935)	(1,612)	(27,968)
Amortization of Acquired Intangible Assets	0	0	0	224
Total Operating Expenses	12,390	8,705	44,728	152,087
Operating Loss	(11,844)	(7,764)	(42,042)	(144,313)
Investment and Other Income, Net	431	521	1,611	1,767
Net Loss Before Income Tax Benefit	(11,413)	(7,243)	(40,431)	(142,546)
Income Tax Benefit				765
Net Loss	$ (11,413)	$ (7,243)	$ (40,431)	$ (141,781)
Basic and Diluted Net Loss Per Common Share	$ (0.75)	$ (0.66)	$ (2.92)	$ (14.12)
Shares Used in Calculating Basic and Diluted Net Loss Per Share	15,282	10,912	13,854	10,042
COMPREHENSIVE LOSS:
Net Loss	$ (11,413)	$ (7,243)	$ (40,431)	$ (141,781)
Other Comprehensive Income (Loss):
Unrealized Gain (Loss) on Marketable Securities	(3)	(8)	52	18
Comprehensive Loss	(11,416)	(7,251)	(40,379)	(141,763)
Product Development and Licensing Agreements
REVENUES:
Total Revenues	55	131	379	2,792
Contracts and Grants
REVENUES:
Total Revenues	$ 491	$ 810	$ 2,307	$ 4,982