CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
REVENUES:
Total Revenues	$ 715	$ 2,763	$ 2,140	$ 6,834
OPERATING EXPENSES:
Research and Development	10,081	21,448	21,232	43,323
General and Administrative	3,908	5,621	8,804	11,215
Goodwill Impairment				90,976
Intangible Asset Impairment				18,677
Other Asset Impairment			1,800
(Gain)/Loss on Fair Value Remeasurement of Contingent Consideration	(1,017)	(7,433)	502	(21,033)
Amortization of Acquired Intangible Assets	0	0	0	224
Total Operating Expenses	12,972	19,636	32,338	143,382
Operating Loss	(12,257)	(16,873)	(30,198)	(136,548)
Investment and Other Income, Net	478	466	1,180	1,245
Net Loss Before Income Tax Benefit	(11,779)	(16,407)	(29,018)	(135,303)
Income Tax Benefit				765
Net Loss	$ (11,779)	$ (16,407)	$ (29,018)	$ (134,538)
Basic and Diluted Net Loss Per Common Share	$ (0.84)	$ (1.67)	$ (2.21)	$ (14.01)
Shares Used in Calculating Basic and Diluted Net Loss Per Share	13,952	9,829	13,129	9,600
COMPREHENSIVE LOSS:
Net Loss	$ (11,779)	$ (16,407)	$ (29,018)	$ (134,538)
Other Comprehensive Income (Loss):
Unrealized Gain on Marketable Securities	36	31	55	26
Comprehensive Loss	(11,743)	(16,376)	(28,963)	(134,512)
Product Development and Licensing Agreements
REVENUES:
Total Revenues	195	1,667	325	2,662
Contracts and Grants
REVENUES:
Total Revenues	$ 520	$ 1,096	$ 1,815	$ 4,172