CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Cash Flows From Operating Activities:
Net Loss	$ (17,239)	$ (118,132)
Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities:
Depreciation and Amortization	1,352	1,028
Amortization of Intangible Assets	0	224
Amortization and Premium of Marketable Securities, Net	(345)	(155)
Loss on Sale or Disposal of Assets	25	10
Goodwill Impairment		90,976
Intangible Asset Impairment		18,677
Other Asset Impairment	1,800
Loss/(Gain) on Fair Value Remeasurement of Contingent Consideration	1,519	(13,600)
Non-Cash Income Tax Benefit		(765)
Stock-Based Compensation Expense	1,693	2,488
Changes in Operating Assets and Liabilities:
Accounts and Other Receivables	855	(1,635)
Prepaid and Other Current Assets	299	(144)
Accounts Payable and Accrued Expenses	(1,455)	(5,919)
Other Liabilities	(1,737)	(1,075)
Net Cash Used in Operating Activities	(13,233)	(28,022)
Cash Flows From Investing Activities:
Sales and Maturities of Marketable Securities	37,886	46,871
Purchases of Marketable Securities	(21,404)	(31,117)
Acquisition of Property and Equipment	(186)	(259)
Net Cash Provided by Investing Activities	16,296	15,495
Cash Flows From Financing Activities:
Net Proceeds from Stock Issuances	4,151	11,689
Proceeds from Issuance of Stock from Employee Benefit Plans	9	374
Net Cash Provided by Financing Activities	4,160	12,063
Net Increase/(Decrease) in Cash and Cash Equivalents	7,223	(464)
Cash and Cash Equivalents at Beginning of Period	24,310	40,288
Cash and Cash Equivalents at End of Period	31,533	39,824
Non-cash Investing Activities
Accrued construction in progress	$ 65	212
Non-cash Supplemental Disclosure
Shares issued to former Kolltan executive for settlement of severance		$ 38