CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
REVENUES:
Total Revenues	$ 1,425	$ 4,068
OPERATING EXPENSES:
Research and Development	11,151	21,875
General and Administrative	4,896	5,593
Goodwill Impairment		90,976
Intangible Asset Impairment		18,677
Other Asset Impairment	1,800
Loss/(Gain) on Fair Value Remeasurement of Contingent Consideration	1,519	(13,600)
Amortization of Acquired Intangible Assets	0	224
Total Operating Expenses	19,366	123,745
Operating Loss	(17,941)	(119,677)
Investment and Other Income, Net	702	780
Net Loss Before Income Tax Benefit	(17,239)	(118,897)
Income Tax Benefit		765
Net Loss	$ (17,239)	$ (118,132)
Basic and Diluted Net Loss Per Common Share	$ (1.40)	$ (12.61)
Shares Used in Calculating Basic and Diluted Net Loss Per Share	12,297	9,370
COMPREHENSIVE LOSS:
Net Loss	$ (17,239)	$ (118,132)
Other Comprehensive Income (Loss):
Unrealized Gain (Loss) on Marketable Securities	19	(5)
Comprehensive Loss	(17,220)	(118,137)
Product Development and Licensing Agreements
REVENUES:
Total Revenues	129	992
Contracts and Grants
REVENUES:
Total Revenues	$ 1,296	$ 3,076