CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
REVENUES:
Total Revenues	$ 4,068	$ 1,534
OPERATING EXPENSES:
Research and Development	21,875	25,793
General and Administrative	5,593	7,229
Goodwill Impairment	90,976
Intangible Asset Impairment	18,677
(Gain)/Loss on Fair Value Remeasurement of Contingent Consideration	(13,600)	3,400
Amortization of Acquired Intangible Assets	224	224
Total Operating Expenses	123,745	36,646
Operating Loss	(119,677)	(35,112)
Investment and Other Income, Net	780	851
Net Loss Before Income Tax Benefit	(118,897)	(34,261)
Income Tax Benefit	765
Net Loss	$ (118,132)	$ (34,261)
Basic and Diluted Net Loss Per Common Share (in dollars per share)	$ (0.84)	$ (0.28)
Shares Used in Calculating Basic and Diluted Net Loss per Share (in shares)	140,548	122,648
COMPREHENSIVE LOSS:
Net Loss	$ (118,132)	$ (34,261)
Other Comprehensive Income (Loss):
Unrealized Gain (Loss) on Marketable Securities	(5)	21
Comprehensive Loss	(118,137)	(34,240)
Product Development and Licensing Agreements
REVENUES:
Total Revenues	992	556
Contracts and Grants
REVENUES:
Total Revenues	$ 3,076	$ 978