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Kolltan Acquisition- Purchase Price (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended
Nov. 29, 2016
Sep. 30, 2017
Dec. 31, 2016
Acquisition-date fair value of consideration transferred      
Fair value of contingent consideration   $ 44,000 $ 44,200
Kolltan      
Kolltan Acquisition      
Shares issued as part of consideration (in shares) 18,257,996    
Shares issuable in lieu of cash severance obligations (in shares) 437,901    
Shares issued in lieu of cash severance obligations (in shares)   91,749  
Remaining obligation (in shares)   125,123  
Closing price of common stock (in dollars per share) $ 4.02    
Acquisition-date fair value of consideration transferred      
Fair value of common stock issued for upfront payment $ 73,397    
Fair value of contingent consideration 44,200    
Kolltan transaction expenses paid in cash by the Company 3,768    
Total consideration transferred 121,365    
Kolltan | Specified development, regulatory approvals or sales-based milestones      
Kolltan Acquisition      
Milestone payments $ 172,500