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Revenue (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2014
Dec. 31, 2016
Revenue            
Deferred revenue $ 3,726   $ 3,726     $ 3,749
Revenues 3,924 $ 2,220 9,287 $ 4,913    
Rockefeller            
Revenue            
Revenues 300 1,100 1,400 1,800    
Bristol-Myers Squibb Company            
Revenue            
Estimated performance period (in years)         5 years  
Deferred revenue         $ 5,000  
Reimbursement of external costs incurred by the company (as a percent)         50.00%  
Revenues 900 $ 500 2,100 $ 1,500    
International AIDS Vaccine Initiative            
Revenue            
Revenues 1,700   4,000      
Frontier Biotechnologies Inc            
Revenue            
Revenues $ 600   $ 600