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Basis of Presentation - (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Basis of Presentation        
Cash, cash equivalents and marketable securities $ 140,500   $ 140,500  
Net Loss $ (26,363) $ (29,598) (89,190) $ (96,223)
Net cash used in operations     $ 80,410 $ 92,687