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Intangible Assets and Goodwill (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Nov. 29, 2016
Intangible Assets and Goodwill            
Goodwill $ 90,976   $ 90,976   $ 90,976  
Finite-lived intangible asset            
Accumulated Amortization (6,951)   (6,951)   (6,503)  
Total Intangible Assets            
Cost of total intangible assets 87,990   87,990   87,990  
Intangible Assets, Net 81,039   81,039   81,487  
Amortization expense for intangible assets 224 $ 254 $ 448 $ 507    
Kolltan            
Intangible Assets and Goodwill            
Goodwill           $ 82,011
Amgen Amendment            
Finite-lived intangible asset            
Estimated Life     16 years      
Cost 14,500   $ 14,500   14,500  
Accumulated Amortization (6,951)   (6,951)   (6,503)  
Net 7,549   7,549   7,997  
IPR&D            
Indefinite-lived intangible assets:            
Indefinite-lived intangible assets 73,490   73,490   $ 73,490  
IPR&D | CuraGen            
Indefinite-lived intangible assets:            
Indefinite-lived intangible assets $ 11,800   $ 11,800      
IPR&D | Kolltan | CDX-0158            
Indefinite-lived intangible assets:            
Fair value of Intangible assets           40,000
IPR&D | Kolltan | CDX-3379            
Indefinite-lived intangible assets:            
Fair value of Intangible assets           3,500
IPR&D | Kolltan | TAM            
Indefinite-lived intangible assets:            
Fair value of Intangible assets           $ 18,000