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Revenue (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
May 31, 2014
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
REVENUE            
Deferred Revenue   $ 3,922   $ 3,922   $ 4,368
Product development and licensing agreements revenue   493 $ 377 1,551 $ 1,053  
Contracts and grants revenue   1,727 649 3,362 2,636  
BMS | PD-1 Immune Checkpoint Inhibitor            
REVENUE            
Term of the agreement 5 years          
Deferred Revenue $ 5,000          
Reimbursement of external costs incurred by the company (as a percent) 50.00%          
Product development and licensing agreements revenue   500 300 1,500 1,000  
Rockefeller            
REVENUE            
Contracts and grants revenue   $ 1,100 $ 500 $ 1,800 $ 2,100