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Revenue (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2014
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Dec. 31, 2015
REVENUE            
Deferred Revenue   $ 4,172   $ 4,172   $ 4,368
Product development and licensing agreements revenue   604 $ 334 1,057 $ 676  
Contracts and grants revenue   785 1,844 1,635 1,988  
BMS | PD-1 Immune Checkpoint Inhibitor            
REVENUE            
Term of the agreement 5 years          
Deferred Revenue $ 5,000          
Reimbursement of external costs incurred by the company (as a percent) 50.00%          
Product development and licensing agreements revenue   600 300 1,000 600  
Rockefeller            
REVENUE            
Contracts and grants revenue   $ 400 $ 1,500 $ 800 $ 1,600