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Basis of Presentation (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Basis of Presentation        
Cash, cash equivalents and marketable securities $ 220,100   $ 220,100  
Net Loss $ (31,952) $ (32,359) (66,625) $ (62,533)
Net cash used in operations     $ (68,732) $ (57,351)