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Net Loss Per Share (Details)
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Anti-dilutive securities    
Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive 6,542,920us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount 5,670,953us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
Stock options    
Anti-dilutive securities    
Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive 6,538,920us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
5,667,953us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Restricted stock    
Anti-dilutive securities    
Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive 4,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_RestrictedStockMember
3,000us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_RestrictedStockMember