CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
REVENUE:
Product Development and Licensing Agreements	$ 200	$ 47	$ 235	$ 77
Contracts and Grants	392	50	773	100
Product Royalties				2,334
Total Revenue	592	97	1,008	2,511
OPERATING EXPENSE:
Research and Development	24,100	15,090	51,169	29,180
Royalty				2,334
General and Administrative	4,787	3,411	9,369	6,549
Amortization of Acquired Intangible Assets	254	254	507	507
Total Operating Expense	29,141	18,755	61,045	38,570
Operating Loss	(28,549)	(18,658)	(60,037)	(36,059)
Investment and Other Income, Net	275	161	1,860	540
Interest Expense		(519)		(829)
Net Loss	(28,274)	(19,016)	(58,177)	(36,348)
Basic and Diluted Net Loss Per Common Share (Note 3) (in dollars per share)	$ (0.32)	$ (0.24)	$ (0.65)	$ (0.47)
Shares Used in Calculating Basic and Diluted Net Loss per Share (Note 3) (in shares)	89,361	80,899	89,316	77,482
COMPREHENSIVE LOSS:
Net Loss	(28,274)	(19,016)	(58,177)	(36,348)
Other Comprehensive (Loss) Income:
Foreign Currency Translation Adjustments	(2)	(1)	(1)	(3)
Unrealized (Loss) Gain on Marketable Securities	80	(140)	81	(194)
Comprehensive Loss	$ (28,196)	$ (19,157)	$ (58,097)	$ (36,545)