CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPRENHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011
REVENUE:
Product Development and Licensing Agreements	$ 40	$ 11	$ 75	$ 25
Contracts and Grants	96		149
Product Royalties	1,873	1,941	4,218	4,443
Total Revenue	2,009	1,952	4,442	4,468
OPERATING EXPENSE:
Research and Development	11,114	7,169	21,881	14,021
Royalty	1,873	1,941	4,218	4,443
General and Administrative	2,219	2,240	4,536	4,576
Amortization of Acquired Intangible Assets	291	483	583	966
Total Operating Expense	15,497	11,833	31,218	24,006
Operating Loss	(13,488)	(9,881)	(26,776)	(19,538)
Investment and Other Income, Net	126	79	331	163
Interest Expense	(411)	(434)	(844)	(920)
Net Loss	(13,773)	(10,236)	(27,289)	(20,295)
Basic and Diluted Net Loss Per Common Share (Note 3) (in dollars per share)	$ (0.23)	$ (0.27)	$ (0.50)	$ (0.58)
Shares Used in Calculating Basic and Diluted Net Loss per Share (Note 3) (in shares)	58,733	37,463	54,439	34,770
COMPREHENSIVE LOSS:
Net Loss	(13,773)	(10,236)	(27,289)	(20,295)
Other Comprehensive (Loss) Income:
Foreign Currency Translation Adjustments	(1)	(1)	1	(5)
Unrealized (Loss) Gain on Marketable Securities	(39)	15	69	28
Comprehensive Loss	$ (13,813)	$ (10,222)	$ (27,219)	$ (20,272)