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Stock-Based Compensation (Details 2) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Valuation and Expenses Information        
Total stock-based compensation expense $ 448 $ 553 $ 1,088 $ 1,133
Stock options
       
Assumptions used for fair values of employee stock options granted        
Expected stock price volatility (as a percent) 71.00% 68.00%   68.00%
Expected stock price volatility,minimum (as a percent)     70.00%  
Expected stock price volatility,maximum (as a percent)     71.00%  
Expected option term 6 years 6 years 6 years 6 years
Risk-free interest rate (as a percent)   2.50%    
Risk-free interest rate, minimum (as a percent) 0.90%   0.90% 2.50%
Risk-free interest rate, maximum (as a percent) 1.30%   1.40% 2.90%
Research and development
       
Valuation and Expenses Information        
Total stock-based compensation expense 284 344 679 705
General and administrative
       
Valuation and Expenses Information        
Total stock-based compensation expense $ 164 $ 209 $ 409 $ 428