CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
REVENUE:
Product Development and Licensing Agreements	$ 40	$ 1,371	$ 65	$ 4,117
Contracts and Grants	5		5	220
Product Royalties	2,318	1,037	6,761	4,735
Total Revenue	2,363	2,408	6,831	9,072
OPERATING EXPENSE:
Research and Development	8,594	7,215	22,615	20,908
Royalty	2,318	1,218	6,761	5,277
General and Administrative	2,273	2,421	6,899	7,848
Gain on Sale of Assets		(50)	(50)	(50)
Amortization of Acquired Intangible Assets	656	483	1,622	2,660
Total Operating Expense	13,841	11,287	37,847	36,643
Operating Loss	(11,478)	(8,879)	(31,016)	(27,571)
Investment and Other Income, Net	144	124	307	3,379
Interest Expense	(438)	(332)	(1,358)	(1,002)
Net Loss	$ (11,772)	$ (9,087)	$ (32,067)	$ (25,194)
Basic and Diluted Net Loss Per Common Share (Note 4) (in dollars per share)	$ (0.27)	$ (0.28)	$ (0.85)	$ (0.79)
Shares Used in Calculating Basic Net Loss per Share (Note 4) (in shares)	44,136	31,922	37,926	31,812
Shares Used in Calculating Diluted Net Loss per Share (Note 4) (in shares)	44,136	31,922	37,926	31,812