CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
REVENUE:
Product Development and Licensing Agreements	$ 11	$ 1,399	$ 25	$ 2,746
Contracts and Grants	0			220
Product Royalties	1,941	1,552	4,443	3,698
Total Revenue	1,952	2,951	4,468	6,664
OPERATING EXPENSE:
Research and Development	7,169	7,256	14,021	13,694
Royalty	1,941	1,732	4,443	4,059
General and Administrative	2,240	2,591	4,626	5,426
Gain on Sale of Assets	0		(50)
Amortization of Acquired Intangible Assets	483	658	966	2,178
Total Operating Expense	11,833	12,237	24,006	25,357
Operating Loss	(9,881)	(9,286)	(19,538)	(18,693)
Investment and Other Income, Net	79	95	163	3,257
Interest Expense	(434)	(334)	(920)	(671)
Net Loss	$ (10,236)	$ (9,525)	$ (20,295)	$ (16,107)
Basic and Diluted Net Loss Per Common Share (Note 4) (in dollars per share)	$ (0.27)	$ (0.30)	$ (0.58)	$ (0.51)
Shares Used in Calculating Basic Net Loss per Share (Note 4) (in shares)	37,463	31,815	34,770	31,755
Shares Used in Calculating Diluted Net Loss per Share (Note 4) (in shares)	37,463	31,815	34,770	31,755