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Income Taxes - Reconciliation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Reconciliation between the amount of reported income tax and the amount computed using U.S. Statutory rate      
Pre-Tax Loss $ (50,878) $ (151,949) $ (117,313)
Loss at Statutory Rates (10,684) (31,909) (39,887)
Difference in Foreign Tax Rates     326
Research and Development Credits (1,902) (2,056) (2,847)
State Taxes (2,170) (6,406) (6,283)
Income Tax Rate Change     99,528
Other (1,011) (1,175) (321)
Change in Fair Value Remeasurement of Contingent Consideration (272) (6,220)  
Intangible Impairment   19,105  
Recognition of APIC NOLs     (5,729)
Impact of Pass-through Entities   (913) (2,775)
Expiration of NOLs and R&D Credit 18,966    
Change in Valuation Allowance $ (2,927) 28,809 (66,294)
Income Tax (Benefit) Provision   $ (765) $ (24,282)