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Summary of Significant Accounting Policies - Property and Equipment (Details)
12 Months Ended
Dec. 31, 2017
Laboratory Equipment  
Property and Equipment  
Estimated useful lives 5 years
Office Furniture and Equipment  
Property and Equipment  
Estimated useful lives 5 years
Computer Equipment  
Property and Equipment  
Estimated useful lives 3 years
Manufacturing Equipment | Minimum  
Property and Equipment  
Estimated useful lives 7 years
Manufacturing Equipment | Maximum  
Property and Equipment  
Estimated useful lives 10 years