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Summary of Significant Accounting Policies - Concentration of Credit Risk- (Details) - Revenue - Customer concentration
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Combined IAVI, Frontier and BMS      
Concentration risk      
Concentration risk (as a percent) 73.00%    
Combined Rockefeller and BMS      
Concentration risk      
Concentration risk (as a percent)   71.00% 86.00%