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STOCK-BASED COMPENSATION - Valuation and Expenses Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Valuation and Expenses Information      
Total stock-based compensation expense $ 15,317 $ 12,774 $ 6,852
Expected dividend payable in foreseeable future $ 0    
Stock options      
Assumptions used for fair values of employee and director stock options granted      
Expected stock price volatility, minimum (as a percent) 70.00% 67.00% 70.00%
Expected stock price volatility, maximum (as a percent) 77.00% 69.00% 72.00%
Expected option term 6 years 6 years 6 years
Risk-free interest rate, minimum (as a percent) 1.40% 1.80% 1.90%
Risk-free interest rate, maximum (as a percent) 2.30% 2.20% 2.20%
Expected dividend yield (as a percent) 0.00% 0.00% 0.00%
Research and development      
Valuation and Expenses Information      
Total stock-based compensation expense $ 7,821 $ 6,186 $ 3,459
General and administrative      
Valuation and Expenses Information      
Total stock-based compensation expense $ 7,496 $ 6,588 $ 3,393