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STOCKHOLDERS' EQUITY (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Stockholders' Equity      
Common stock issued (in shares) 8,337,500   21,613,483
Net proceeds from sale of common stock $ 188,840   $ 295,697
Net proceeds from sale of stock in an underwritten public offering $ 188,840   278,563
Preferred stock, shares authorized 3,000,000 3,000,000  
Shares common stock issued in connection with supply agreement 98,685,595 89,592,779  
Shares Issued in Connection with Supply Agreement   $ 2,000  
Research and Development expense $ 100,171 $ 104,381 67,401
Biosyn Corporation      
Stockholders' Equity      
Shares common stock issued in connection with supply agreement   152,172  
Shares Issued in Connection with Supply Agreement   $ 2,000  
Research and Development expense   $ 2,000  
Underwritten Public Offering      
Stockholders' Equity      
Net proceeds from sale of stock in an underwritten public offering $ 188,800   $ 278,600
Class C Preferred Stock      
Stockholders' Equity      
Preferred stock, shares authorized 3,000,000    
Series C-1 Preferred Stock      
Stockholders' Equity      
Preferred stock, shares authorized 350,000    
Cantor Amendment      
Stockholders' Equity      
Common stock issued (in shares)     2,433,608
Net proceeds from sale of common stock     $ 17,100