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INCOME TAXES (Details 2) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards 8,000,000us-gaap_OperatingLossCarryforwards  
Number of states in which the entity primarily operates or has operated and has income tax nexus 3us-gaap_NumberOfStatesInWhichEntityOperates  
Unrecognized tax benefits 0us-gaap_UnrecognizedTaxBenefits 0us-gaap_UnrecognizedTaxBenefits
CuraGen    
Net operating loss and tax credit carryforwards    
Assets recorded for net operating losses not yet utilized 0cldx_DeferredTaxAssetsOperatingLossCarryforwardsNotYetUtilized
/ us-gaap_BusinessAcquisitionAxis
= cldx_CuraGenCorporationMember
 
Federal    
Net operating loss and tax credit carryforwards    
Period of recognition of unrealized loss or gain after the ownership change 5 years  
Federal | R&D credit    
Net operating loss and tax credit carryforwards    
Tax credit carryforwards 20,800,000us-gaap_TaxCreditCarryforwardAmount
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ us-gaap_TaxCreditCarryforwardAxis
= us-gaap_ResearchMember
 
Tax credit carryforwards with substantial limitations on use 23,600,000cldx_TaxCreditCarryforwardAmountWithSubstantialLimitationsOnUse
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ us-gaap_TaxCreditCarryforwardAxis
= us-gaap_ResearchMember
 
Federal | Ownership change in October 2007    
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards 28,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_OwnershipChangeAxis
= cldx_OwnershipChangeInOctober2007Member
 
Annual limitation 4,500,000cldx_OperatingLossCarryforwardsAnnualLimitationAmount
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_OwnershipChangeAxis
= cldx_OwnershipChangeInOctober2007Member
 
Federal | Ownership changes in June 2009 and December 2009    
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards 67,700,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_OwnershipChangeAxis
= cldx_OwnershipChangesInJune2009AndDecember2009Member
 
Annual limitation 6,000,000cldx_OperatingLossCarryforwardsAnnualLimitationAmount
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_OwnershipChangeAxis
= cldx_OwnershipChangesInJune2009AndDecember2009Member
 
Federal | Prior to merger    
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards 33,000,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_StatusOfMergerAndAcquisitionAxis
= cldx_PriorToMergerMember
 
Federal | CuraGen | Prior to acquisition    
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards 518,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_BusinessAcquisitionAxis
= cldx_CuraGenCorporationMember
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_StatusOfMergerAndAcquisitionAxis
= cldx_PriorToAcquisitionMember
 
Federal | AVANT    
Net operating loss and tax credit carryforwards    
Net operating loss carryforwards   182,000,000us-gaap_OperatingLossCarryforwards
/ us-gaap_BusinessAcquisitionAxis
= cldx_AVANTMember
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
Loss carryforwards with limitations on use 40,400,000cldx_OperatingLossCarryforwardsWithLimitationsOnUse
/ us-gaap_BusinessAcquisitionAxis
= cldx_AVANTMember
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
 
Loss carryforwards remotely likely to be utilized in future periods 60,800,000cldx_OperatingLossCarryforwardsRemotelyLikelyToBeUtilized
/ us-gaap_BusinessAcquisitionAxis
= cldx_AVANTMember
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
 
Federal | AVANT | Prior to merger    
Net operating loss and tax credit carryforwards    
NOL, net of expirations and utilization 101,200,000cldx_OperatingLossCarryforwardsNetOfExpirationsAndUtilization
/ us-gaap_BusinessAcquisitionAxis
= cldx_AVANTMember
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
/ cldx_StatusOfMergerAndAcquisitionAxis
= cldx_PriorToMergerMember
 
State    
Net operating loss and tax credit carryforwards    
Tax credit carryforwards with substantial limitations on use 127,600,000cldx_TaxCreditCarryforwardAmountWithSubstantialLimitationsOnUse
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_StateAndLocalJurisdictionMember
 
State | R&D credit    
Net operating loss and tax credit carryforwards    
Tax credit carryforwards 14,400,000us-gaap_TaxCreditCarryforwardAmount
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_StateAndLocalJurisdictionMember
/ us-gaap_TaxCreditCarryforwardAxis
= us-gaap_ResearchMember
 
Tax credit carryforwards with substantial limitations on use 9,300,000cldx_TaxCreditCarryforwardAmountWithSubstantialLimitationsOnUse
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_StateAndLocalJurisdictionMember
/ us-gaap_TaxCreditCarryforwardAxis
= us-gaap_ResearchMember