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STOCK-BASED COMPENSATION (Details 2) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Valuation and Expenses Information      
Total stock-based compensation expense (in dollars) $ 6,852us-gaap_AllocatedShareBasedCompensationExpense $ 4,548us-gaap_AllocatedShareBasedCompensationExpense $ 2,298us-gaap_AllocatedShareBasedCompensationExpense
Assumptions used for fair values of employee and director stock options granted      
Expected dividend payable in foreseeable future 0cldx_ExpectedDividendPayableInForeseeableFuture    
Stock options      
Assumptions used for fair values of employee and director stock options granted      
Expected stock price volatility, minimum (as a percent) 70.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
71.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
70.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Expected stock price volatility, maximum (as a percent) 72.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
72.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
72.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Expected option term 6 years 6 years 6 years
Risk-free interest rate, minimum (as a percent) 1.90%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
1.20%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
0.90%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Risk-free interest rate, maximum (as a percent) 2.20%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
2.10%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
1.40%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Expected dividend yield (as a percent) 0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= cldx_EmployeeConsultantAndNonEmployeeDirectorStockOptionMember
Research and development      
Valuation and Expenses Information      
Total stock-based compensation expense (in dollars) 3,459us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember
2,640us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember
1,415us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember
General and administrative      
Valuation and Expenses Information      
Total stock-based compensation expense (in dollars) $ 3,393us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_GeneralAndAdministrativeExpenseMember
$ 1,908us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_GeneralAndAdministrativeExpenseMember
$ 883us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_GeneralAndAdministrativeExpenseMember