PROPERTY AND EQUIPMENT, NET (Details) (USD $) In Thousands, unless otherwise specified	12 Months Ended
Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Property and equipment
Total Property and Equipment	$ 19,530	$ 19,463
Less Accumulated Depreciation and Amortization	(12,325)	(10,370)
Property and Equipment, Net	7,205	9,093
Depreciation and amortization expense	2,047	2,248	2,718
Laboratory Equipment
Property and equipment
Total Property and Equipment	3,164	2,630
Manufacturing Equipment
Property and equipment
Total Property and Equipment	2,055	1,999
Office Furniture and Equipment
Property and equipment
Total Property and Equipment	1,264	1,314
Leasehold Improvements
Property and equipment
Total Property and Equipment	12,932	13,280
Construction in Progress
Property and equipment
Total Property and Equipment	$ 115	$ 240

The cumulative amount of depreciation, depletion and amortization (related to property, plant and equipment, but not including land) that has been recognized in the income statement.

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Gross amount of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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- Definition

Amount, net of accumulated depreciation, depletion and amortization, of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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