Exhibit 32.1

Certification of Chief Executive Officer and Chief Financial Officer Pursuant to Rule 13a – 14(a) of the Securities Exchange Act of 1934 and 18 U.S.C., Section 1350, as adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

I hereby certify that the accompanying Annual Report of MidWestOne Financial Group, Inc. on Form 10-K for the year ended December 31, 2004 fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 and that information contained in such Report fairly presents, in all material respects, the financial condition and results of operations of MidWestOne Financial Group, Inc.

Date: March 30, 2005	/s/    CHARLES S. HOWARD
	Charles S. Howard
	President and Chief Executive Officer
	/s/    DAVID A. MEINERT
	David A. Meinert
	Executive Vice President and
	Chief Financial Officer