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Stock-based Compensation (Tables)
9 Months Ended
Sep. 30, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Allocated Stock-based Compensation


For the three months ended
September 30,


For the nine months ended
September 30,



2011


2012


2011


2012

General and administrative

$ 234,185

$ 38,719

$ 1,915,969

$ 158,947
Research and development


51,934


22,696


157,024


96,054

















Total

$ 286,119

$ 61,415

$ 2,072,993

$ 255,001
Schedule of Unrecognized Compensation Expense




2012

$ 42,572
2013


164,085
2014


79,224
2015


892
Total

$ 286,733
Schedule of Option and Warrant Activity


Options
and
Warrants
Outstanding


Weighted
Average
Exercise
Price








Outstanding at December 31, 2011


20,440,551

$ 1.10
Options granted


50,000


0.37
Warrants issued


24,317,900


0.33
Expired


(140,169 )

1.31
Forfeited


(1,464,419 )

1.35
Exercised


--


--









Outstanding at September 30, 2012


43,203,863

$ 0.52
Schedule of Information About Stock Options and Warrants



Outstanding


Exercisable







Weighted
Average
Remaining


Weighted
Average





Weighted
Average

Range of
Exercise Prices


Number
Outstanding


Contractual
Life (years)


Exercise
Price


Number
Exercisable


Exercise
Price

$ 0.17-0.95


39,173,684


4.62

$ 0.43


38,728,684

$ 0.43

1.00-1.65


3,411,179


3.60


1.04


3,207,646


1.04

2.25-5.00


619,000


2.98


3.05


619,000


3.05
$ 0.17-5.00


43,203,863


4.52

$ 0.52


42,555,330

$ 0.51
Schedule of Restricted Stock Unit Activity


Restricted
Stock Units


Weighted
Average
Grant
Date Fair
Value








Outstanding at December 31, 2011


2,550,000

$ 1.25
Awarded at fair value


202,633


0.25
Canceled/Forfeited


--


--
Settled by issuance of stock


--


--
Outstanding at September 30, 2012


2,752,633

$ 1.18
Vested at September 30, 2012


2,752,633

$ 1.18
Stock Options [Member]
 
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Assumptions Used to Value Awards


Nine Months Ended
September 30, 2011


Nine Months Ended
September 30, 2012
Risk free interest rate


1.96 %


1.65 %
Expected life (in years)


6.28



10.0
Expected volatility


81.03 %


78.97 %
Expected dividend yield


0.00 %


0.00 %
Warrant [Member]
 
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Assumptions Used to Value Awards


Nine Months Ended
September 30, 2011


Nine Months Ended
September 30, 2012
Risk free interest rate


2.04 %


1.17 %
Expected life (in years)


5.00



5.76
Expected volatility


85.82 %


82.78 %
Expected dividend yield


0.00 %


0.00 %