FORM 10-Q

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

(Mark One)

(X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2011

OR

(  ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period                                                                                      to                                           

Commission file number 1-11394

MEDTOX SCIENTIFIC, INC.

(Exact name of registrant as specified in its charter)

Delaware	95-3863205
(State or other jurisdiction of	(I.R.S. Employer
incorporation or organization)	Identification No.)

402 West County Road D, St. Paul, Minnesota	55112
(Address of principal executive offices)	(Zip Code)

Registrant's telephone number including area code:                                                                                        (651) 636-7466

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes [ X ]                      No [   ]

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

                                                                                                Yes [   ]                      No [   ]                      

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer, or a smaller reporting company.  See definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer [   ]                      Accelerated filer [ X ]                   Non-accelerated filer [  ]                  Smaller reporting company  [   ]

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes [   ]                      No [ X ]

Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest practicable date:

Class	Outstanding at April 15, 2011
Common Stock, $0.15 par value per share	8,919,428

MEDTOX SCIENTIFIC, INC.

INDEX

			Page
Part I	Financial Information:
	Item 1:	Financial Statements (Unaudited)
		Consolidated Statements of Income – Three
		Months Ended March 31, 2011 and 2010	3
		Consolidated Balance Sheets – March 31, 2011
		and December 31, 2010	4
		Consolidated Statements of Cash Flows – Three
		Months Ended March 31, 2011 and 2010	5
		Notes to Consolidated Financial Statements	6
	Item 2:	Management's Discussion and Analysis of
		Financial Condition and Results of Operations	10
	Item 3:	Quantitative and Qualitative Disclosures
		About Market Risk	20
	Item 4:	Controls and Procedures	20
Part II	Other Information		21
	Item 1A:	Risk Factors	21
	Item 2:	Unregistered Sales of Equity Securities and Use of Proceeds	21
	Item 5:	Other Information	21
	Item 6:	Exhibits	22
		Signatures	23
		Exhibit Index	24

- 2 -

PART I                FINANCIAL INFORMATION

Item 1:                 FINANCIAL STATEMENTS(UNAUDITED)

MEDTOX SCIENTIFIC, INC.

CONSOLIDATED STATEMENTS OF INCOME

(In thousands, except share and per share data)

(Unaudited)

	Three Months Ended
	March 31, 2011			March 31, 2010
REVENUES:
Laboratory services:
Drugs-of-abuse testing services	$	9,640		$	8,796
Clinical & other laboratory services		7,975			6,890
Clinical trial services		2,536			833
Product sales		5,585			4,642
		25,736			21,161
COST OF REVENUES:
Cost of services		12,952			11,033
Cost of sales		2,333			2,028
		15,285			13,061
GROSS PROFIT		10,451			8,100
OPERATING EXPENSES:
Selling, general and administrative		8,624			7,433
Research and development		594			549
		9,218			7,982
INCOME FROM OPERATIONS		1,233			118
OTHER INCOME (EXPENSE):
Interest expense		(24	)		(1	)
Other income		16			5
		(8	)		4
INCOME BEFORE INCOME TAX EXPENSE		1,225			122
INCOME TAX EXPENSE		(447	)		(45	)
NET INCOME	$	778		$	77
BASIC EARNINGS PER COMMON SHARE	$	0.09		$	0.01
DILUTED EARNINGS PER COMMON SHARE	$	0.09		$	0.01
WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING:
Basic		8,850,228			8,632,574
Diluted		9,043,757			8,847,337

See Notes to Consolidated Financial Statements (Unaudited).

- 3 -

MEDTOX SCIENTIFIC, INC.

CONSOLIDATED BALANCE SHEETS

(In thousands, except share and per share data)

(Unaudited)

	March 31, 2011			December 31, 2010
ASSETS
CURRENT ASSETS:
Cash and cash equivalents	$	1,032		$	1,285
Accounts receivable:
Trade, less allowance for doubtful accounts ($1,911 in 2011 and $1,592 in 2010)		19,608			18,618
Other		571			957
Total accounts receivable		20,179			19,575
Inventories		4,081			3,902
Prepaid expenses		1,648			1,532
Deferred income taxes		3,348			3,765
Total current assets		30,288			30,059
BUILDING, EQUIPMENT AND IMPROVEMENTS, net		28,163			28,164
GOODWILL		15,967			15,967
OTHER INTANGIBLE ASSETS, net		186			198
OTHER ASSETS		1,015			1,069
TOTAL ASSETS	$	75,619		$	75,457
LIABILITIES AND STOCKHOLDERS’ EQUITY
CURRENT LIABILITIES:
Line of credit	$	3,685		$	2,725
Accounts payable		4,962			4,079
Accrued expenses		5,721			7,101
Total current liabilities		14,368			13,905
LONG-TERM LIABILITIES		4,108			3,871
DEFERRED INCOME TAXES, net		3,562			3,562
STOCKHOLDERS' EQUITY:
Preferred stock, $1.00 par value; authorized shares, 50,000; none issued and outstanding		-			-
Common stock, $0.15 par value; authorized shares, 28,000,000; issued shares, 9,022,888
in 2011 and 2010		1,353			1,353
Additional paid-in capital		78,497			78,425
Accumulated deficit		(19,128	)		(19,906	)
Common stock held in trust, at cost, 517,571 shares in 2011 and 428,596 shares in 2010		(6,141	)		(4,753	)
Treasury stock, at cost, 103,460 shares in 2011 and 2010		(1,000	)		(1,000	)
Total stockholders' equity		53,581			54,119
TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY	$	75,619		$	75,457

See Notes to Consolidated Financial Statements (Unaudited).

- 4 -

MEDTOX SCIENTIFIC, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS

(In thousands)

(Unaudited)

	Three Months Ended
	March 31, 2011			March 31, 2010
CASH FLOWS PROVIDED BY OPERATING ACTIVITIES:
Net income	$	778		$	77
Adjustments to reconcile net income to net cash provided by
operating activities:
Depreciation and amortization		1,496			1,420
Provision for losses on accounts receivable		678			230
Deferred and stock-based compensation		325			244
Deferred income taxes		417			45
Changes in operating assets and liabilities:
Accounts receivable		(1,282	)		(1,660	)
Inventories		(179	)		(4	)
Prepaid expenses		(116	)		(97	)
Other assets		17			17
Accounts payable and accrued expenses		(832	)		649
Net cash provided by operating activities		1,302			921
CASH FLOWS USED IN INVESTING ACTIVITIES:
Purchase of building, equipment and improvements		(1,127	)		(1,048	)
Net cash used in investing activities		(1,127	)		(1,048	)
CASH FLOWS (USED IN) PROVIDED BY FINANCING ACTIVITIES:
Proceeds from line of credit		9,090			-
Payments on line of credit		(8,130	)		-
Principal payments on long-term debt		-			(169	)
Purchase of common stock for incentive plan		(1,388	)		-
Net proceeds from the exercise of stock options		-			579
Net cash (used in) provided by financing activities		(428	)		410
(DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS		(253	)		283
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD		1,285			4,165
CASH AND CASH EQUIVALENTS AT END OF PERIOD	$	1,032		$	4,448
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
Cash paid for:
Interest	$	24		$	1
Income taxes		113			25
Supplemental noncash activities:
Asset additions and related obligations in payables	$	867		$	118

See Notes to Consolidated Financial Statements (Unaudited).

- 5 -

MEDTOX SCIENTIFIC, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED)

March 31, 2011

1.  BASIS OF PRESENTATION

The accompanying unaudited consolidated financial statements of MEDTOX Scientific, Inc. (the Company) have been prepared in accordance with accounting principles generally accepted in the United States of America for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X.  Accordingly, they do not include all of the information and notes required by generally accepted accounting principles.  In the opinion of management, all adjustments (consisting only of normal recurring adjustments) considered necessary for a fair presentation of financial condition and results of operations have been included.  Operating results for the three month period ended March 31, 2011 are not necessarily indicative of the results that may be attained for the entire year.  These consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto included in the Company's Annual Report on Form 10-K for the year ended December 31, 2010.

2.  SEGMENTS

The Company has two reportable segments:  Laboratory Services and Product Sales.  The Laboratory Services segment consists of MEDTOX Laboratories, Inc. and New Brighton Business Center, LLC (NBBC).  Services provided include drugs-of-abuse testing services; clinical & other laboratory services, which include clinical toxicology, clinical testing for occupational health clinics, clinical testing for physician offices, pediatric lead testing, heavy metals analyses, courier delivery, and medical surveillance; and clinical trial services which include central laboratory services, assay development, bio-analytical, bio-equivalence and pharmacokinetic testing.  The Product Sales segment, which includes POCT (point-of-collection testing) disposable diagnostic devices, consists of MEDTOX Diagnostics, Inc.  Products manufactured include easy to use, inexpensive, on-site drug tests such as PROFILE®-II, PROFILE®-II A, PROFILE®-III, PROFILE®-III A, PROFILE-II ER®, PROFILE®-III ER, PROFILE®-IV, PROFILE®-V, MEDTOXScan®, VERDICT®-II and SURE-SCREEN®, in addition to a variety of other diagnostic tests for the detection of alcohol.  MEDTOX Diagnostics also provides contract manufacturing services in its Food and Drug Administration (FDA) registered/ISO 13845 certified facility.

The Company’s reportable segments are strategic business units that offer different products and services. They are managed separately as each business requires different products, services and marketing strategies.

In evaluating financial performance, management focuses on income from operations as a segment’s measure of profit or loss.

- 6 -

(In thousands)	Three Months Ended
	March 31, 2011			March 31,  2010
Laboratory Services:
Revenues	$	20,151		$	16,519
Depreciation and amortization		1,296			1,223
Income (loss) from operations		102			(561	)
Capital expenditures for segment assets		793			1,001
Product Sales:
Revenues	$	5,585		$	4,642
Depreciation and amortization		200			197
Income from operations		1,131			679
Capital expenditures for segment assets		334			47
Corporate (unallocated):
Other income (expense)	$	(8	)	$	4
Company:
Revenues	$	25,736		$	21,161
Depreciation and amortization		1,496			1,420
Income from operations		1,233			118
Other income (expense)		(8	)		4
Income before income tax expense		1,225			122
Capital expenditures for assets		1,127			1,048

(In thousands)	March 31, 2011		December 31, 2010
Assets:
Laboratory Services	$	64,219	$	64,193
Product Sales		8,052		7,499
Corporate (unallocated)		3,348		3,765
Company	$	75,619	$	75,457

The following is a summary of revenues from external customers for each group of products and services provided within the Product Sales segment:

(In thousands)	Three Months Ended
	March 31, 2011		March 31, 2010
POC on site testing products	$	4,859	$	4,109
Contract manufacturing services		536		395
Other diagnostic products		190		138
	$	5,585	$	4,642

- 7 -

3.  INVENTORIES

Inventories consisted of the following:

(In thousands)	March 31, 2011		December 31, 2010
Raw materials	$	848	$	786
Work in process		416		406
Finished goods		299		390
Supplies, including off-site inventory		2,518		2,320
	$	4,081	$	3,902

4.  EARNINGS PER SHARE

The following table sets forth the computation of basic and diluted earnings per common share:

(In thousands, except share and per share data)	Three Months Ended
	March 31, 2011		March 31, 2010
Net income (A)	$	778	$	77
Weighted average number of basic common shares outstanding (B)		8,850,228		8,632,574
Dilutive effect of stock options computed based on the treasury stock method using average market price		193,529		214,763
Weighted average number of diluted common shares outstanding (C)		9,043,757		8,847,337
Basic earnings per common share (A/B)	$	0.09	$	0.01
Diluted earnings per common share (A/C)	$	0.09	$	0.01

5.  INCOME TAXES

At December 31, 2010, the Company had federal net operating loss carryforwards (NOLs) of approximately $4.8 million, which are available to offset future taxable income.  The Company's federal NOLs expire in varying amounts each year from 2023 through 2029 in accordance with applicable federal tax regulations and the timing of when the NOLs were incurred.  Section 382 of the Internal Revenue Code restricts the annual utilization of certain NOLs incurred prior to a change in ownership.  However, such limitation is not expected to impair the realization of these NOLs.  In the future, subsequent revisions to the estimated net realizable value of these deferred tax assets could cause the provision for income taxes to vary significantly from period to period, although the Company’s cash payments would remain unaffected until the benefit of the NOLs is completely utilized or expires unused.

- 8 -

6.  CONTINGENCIES

Leases - The Company leases offices and facilities and office equipment under certain operating leases, which expire on various dates through March 2016.  Under the terms of the facility leases, a pro rata share of operating expenses and real estate taxes are charged as additional rent.

Legal - The Company is party to various legal proceedings arising in the normal course of business activities, none of which, in the opinion of management, are expected to have a material adverse impact on the Company's consolidated financial position or results of operations.

- 9 -

Item 2:  MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

This Form 10-Q contains certain forward looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, which are intended to be covered by the safe harbors created by such acts.  For this purpose, any statements that are not statements of historical fact may be deemed to be forward looking statements, including the statements under “Management’s Discussion and Analysis of Financial Condition and Results of Operations” regarding our strategy, future operations, future expectations and future estimates, future financial position or results, and future plans and objectives of management.  Those statements in this Form 10-Q containing the words “believes”, “anticipates”, “plans”, “expects”, and similar expressions constitute forward looking statements, although not all forward looking statements contain such identifying words.  Examples of forward looking statements include, but are not limited to (i) projections of, or statements regarding, future revenues, income or loss, earnings or loss per share, capital expenditures, dividends, capital structure, margins and other financial items, (ii) statements regarding our plans and objectives and the impacts thereof, including planned introductions of new products and services, planned exiting of lines of business and planned regulatory filings, or estimates or predictions of actions by customers, suppliers, competitors or regulatory authorities, (iii) estimates of market sizes and market opportunities, (iv) statements regarding economic conditions, (v) statements regarding the sufficiency of our existing resources to fund our planned operations through 2011 and the sufficiency of future profitable operations and access to additional capital to fund our operations beyond 2011, and (vi) statements of assumptions underlying other statements and statements about our business.

The forward looking statements contained in this Form 10-Q are based on our current expectations, assumptions, estimates and projections about our Company and its businesses.  All such forward looking statements involve significant risks and uncertainties, including those risks identified in the next paragraph, many of which are beyond our control.  Although we believe that the assumptions underlying our forward looking statements are reasonable, any of the assumptions could prove inaccurate.  Actual results may differ materially from those indicated by the forward looking statements included in this Form 10-Q.  In light of the significant uncertainties inherent in the forward looking statements included in this Form 10-Q, you should not consider the inclusion of such information as a representation by us or anyone else that we will achieve such results.  Moreover, we assume no obligation to update these forward looking statements to reflect actual results or changes in assumptions, expectations, or projections.  In addition, our financial and performance outlook concerning future revenues, margins, earnings, earnings per share, and other operating or performance results does not include the impact of any future acquisitions, future acquisition-related expenses or accruals, or any future restructuring or other charges that may occur from time to time due to management decisions and changing business circumstances and conditions.

The following is a listing of some of the important factors that could cause actual results to differ materially from those indicated by the forward looking statements contained in this Form 10-Q:

·   changes in federal, state, local and third party payer regulations or policies or other future reforms in the health care system (or in the interpretation of current regulations), affecting governmental and third-party coverage or reimbursement for  laboratory testing

- 10 -

·   loss or suspension of a license or imposition of a fine or penalties under, or future changes in, or interpretations of, the law or regulations of the Clinical Laboratory Improvement Act of 1967, the Clinical Laboratory Improvement Amendments of 1988, the Substance Abuse and Mental Health Services Administration (SAMHSA), or those of Medicare, Medicaid, the False Claims Act or other federal, state or local agencies

·   failure to comply with HIPAA (Health Insurance Portability and Accountability Act), including changes to federal and state privacy and security obligations and changes to HIPAA, including those changes included within HITECH (Health Information Technology for Economic and Clinical Health) and any subsequent amendments, which could result in increased costs, denial of claims and/or significant penalties

·   failure to maintain the security of customer-related information could damage the Company’s reputation with customers, cause it to incur substantial additional costs and become subject to litigation

·   changes in FDA (Food and Drug Administration) regulations or policies (or in the interpretation of current regulations) affecting laboratory developed tests and the 510(k) clearance process

·   increased competition, including price competition

·   changes in demand for our services and products by our customers

·   changes in general economic and business conditions, both nationally and internationally, which can influence the level of job growth and, in turn, the level of pre-employment drug screening activity

·   technological or regulatory developments, or evolving industry standards, that could affect or delay the sale of our products

·   our ability to attract and retain experienced and qualified personnel

·   risks and uncertainties with respect to our patents and proprietary rights, including:

o   other companies challenging our patents

o   patents issued to other companies that may harm our ability to do business

o   other companies designing around technologies we have developed

o   our inability to obtain appropriate licenses from third parties

o   our inability to protect our trade secrets

o   risk of infringement upon the proprietary rights of others

o   our inability to prevent others from infringing on our proprietary rights

·   our inability to control the costs in our business

·   our inability to obtain sufficient financing to continue to sustain or expand our operations

·   adverse results in litigation matters

- 11 -

·   our inability to continue to develop innovative products and services

·   our inability to provide our services in a timely manner

·   an unforeseen decrease in the acceptance of current new products and services, including in the market for clinical laboratory testing for physicians offices and patients

·   fluctuations in clinical trial activities

·   inaccurate information regarding market opportunities

·   failure to receive regulatory approvals and clearances

·   other factors, including those set forth in Item 1A of our Annual Report on Form 10-K for the year ended December 31, 2010

The above listing should not be construed as exhaustive; we cannot predict all the factors that could cause results to differ materially from those indicated by the forward looking statements.

Executive Overview

Our Business

We are engaged primarily in distinct, but very much related businesses, which for financial reporting purposes are divided into two reportable segments: Laboratory Services and Product Sales. For financial information relating to our segments, see Note 2 of Notes to the Consolidated Financial Statements.

Laboratory Services

Our “Laboratory Services” business segment includes the activities of our wholly-owned subsidiary, MEDTOX Laboratories, Inc.  MEDTOX Laboratories, Inc. engages in drugs-of-abuse testing services, providing these services to private and public companies, drug treatment counseling centers, criminal justice facilities, occupational health clinics and hospitals, as well as third party administrators.

MEDTOX Laboratories, Inc. also provides clinical and other laboratory services which consist of clinical toxicology, clinical testing for occupational health clinics, and heavy metal, trace element and solvent analyses.  We provide these services to hospitals, clinics, HMOs and other laboratories.  Testing is conducted using methodologies that include various immunoassays, gas liquid chromatography, gas chromatography/mass spectrometry, and high performance liquid chromatography with tandem mass spectrometry.  We recently expanded our clinical & other laboratory services to include laboratory tests used by physicians and other healthcare providers for the purpose of diagnosing or treating disease or illness or the assessment of health in humans.  Testing is performed on blood, body fluids or tissues.  Our comprehensive clinical laboratory services include clinical chemistry, hematology, coagulation, urinalysis, immunology/serology (viruses, infectious diseases, immune system), immunohematology (blood typing, antibody screens), microbiology (bacteria, parasites), anatomical pathology/cytology (tissue biopsies, cancer), molecular diagnostics (infectious diseases, genetic disorders) and sub-specialties of these categories.  We also provide services in the areas of logistics management, data management and program management.  These services support our underlying business of laboratory analysis and provide added value to our clients.

- 12 -

MEDTOX Laboratories, Inc. also provides clinical trial services which includes central laboratory services, assay (test) development, bio-analytical, bio-equivalence and pharmacokinetic testing.  Central laboratory services include tests that are used to monitor the safety and efficacy of a drug.  These tests or “safety labs” include tests that are performed in our general clinical laboratory and pathology laboratory such as clinical chemistries (liver function, kidney function, cardiac and bone), hematology (blood count), immunology (immune status), and flow cytometry (cell identification).  Assay development, bio-analytical and bio-equivalence studies are performed in our bio-analytical laboratory.  These tests are conducted using methodologies such as immunoassay, gas chromatography, high performance liquid chromatography, gas chromatography/mass spectrometry and tandem mass spectrometry.  Clients for our clinical testing services include clinical trial sponsors (pharmaceutical and biotech companies), clinical research organizations (CROs), research organizations, and investigators with trial management, patient recruitment/enrollment and site management.

The New Brighton Business Center, LLC (NBBC) is a wholly-owned limited liability company formed for the sole purpose of acquiring the facilities in St. Paul, Minnesota, where our Laboratory Services administrative offices and laboratory operations are located.

Product Sales

Our “Product Sales” business segment consists of our wholly-owned subsidiary, MEDTOX Diagnostics, Inc.  MEDTOX Diagnostics, Inc. is engaged in the development, manufacturing, and distribution of a variety of POCT diagnostic drug screening devices, such as our PROFILE®-II, PROFILE®-II A, PROFILE®-III, PROFILE®-III A, PROFILE-II ER®, PROFILE®-III ER, PROFILE®-IV, PROFILE®-V, MEDTOXScan® reader, VERDICT®-II, and SURE-SCREEN® products, in addition to other diagnostic tests for the detection of alcohol.  MEDTOX Diagnostics, Inc. also provides contract manufacturing services, such as coagulation market controls.  The operations of the Product Sales segment are located in Burlington, North Carolina, where we maintain the offices, research and development laboratories, production operations, and warehouse/distribution facilities.

Key Trends Influencing Our Operating Results

Our management believes that there are several notable trends that are currently influencing, and are expected in the foreseeable future to continue to influence, our operating results.  These include:

Economic Uncertainties Causing Variability in Testing Volumes in the Drugs-of-Abuse Business

In the first quarter of 2011, testing volume from our existing workplace drugs-of-abuse clients was lower than in the prior year period, which we primarily attributed to lower new job creation and reduced employment levels and corresponding drops in hiring caused by economic uncertainties.  We feel economic uncertainties may continue to cause variability in our workplace drugs-of-abuse testing volume in the foreseeable future.

- 13 -

Increased POCT Diagnostic Device Test Competition

We have experienced increased competition with respect to our POCT diagnostic tests from systems and products developed by others, many of whom compete solely on price.  We have continued to experience increased price competition for certain diagnostic testing devices, particularly in the probation, parole and rehabilitation market.

Our Strategy

Our strategy is to drive profitable growth by building market share, leveraging our existing infrastructure and technical expertise, and driving innovation.  We maintain a disciplined culture, focused on the successful execution of our strategy and plans.

Building Market Share

We have solid niche positions in large markets, relative to our size, that allow us to build market share by offering high quality products and services that are delivered rapidly, priced competitively, and supported by excellent customer service and value-added services.  Our value added services include data management, collection site management, training, technical support and expertise, as well as review of drug testing policies for clients.

Our success in penetrating new accounts has represented a significant component of our growth in market share.  Over the past few years, we have expanded our number of sales representatives which has increased our business from new accounts and helps offset risks from uncertain economic conditions that may cause lower activity from existing workplace drugs-of-abuse clients.

Leveraging Existing Infrastructure and Technical Expertise

We leverage our existing infrastructure and technical expertise to facilitate top line growth and improve operating margins.

We expanded our clinical laboratory capabilities to include clinical and anatomic pathology, microbiology, molecular diagnostics, and other specialized testing capabilities.  This expansion leverages existing capabilities and opens up new revenue opportunities by offering full-service testing capabilities to the physician office market.

Our LEAN and Six-Sigma initiatives support our effort to leverage existing infrastructure by improving quality and productivity, cutting costs, and increasing throughput.  LEAN is a highly disciplined process that helps us focus on reducing waste and eliminating unnecessary steps in our business processes.  Our Six-Sigma initiatives address quality and variability within processes. While all key departments in the Laboratory Services and Product Sales segments have now been through initial LEAN processes, as an organization we recognize that LEAN is an ongoing philosophy, not a project to be “finished.”

Driving Innovation

We have introduced a number of innovative products and services.

- 14 -

In 2011 and 2010, we continued the expansion of our Prescription management business.  We offer a comprehensive testing program serving this market under the name ToxAssure®.

In 2009, we introduced the next generation PROFILE®-V MEDTOXScan® Drugs-of-Abuse Test System with added functionality for hospital laboratories and emergency rooms.

Critical Accounting Policies

There were no significant changes to our critical accounting policies during the quarter ended March 31, 2011 from those disclosed in our Annual Report on Form 10-K for the year ended December 31, 2010.

Results of Operations

In evaluating our financial performance, our management has primarily focused on the following objectives: revenue growth, maximizing operating income, increasing our cash flows and strengthening our balance sheet.  The first two of these objectives are discussed in this section.  The other two are addressed under “Liquidity and Capital Resources.”

To maximize our operating income, we have sought revenue growth, improved gross margin and reduced selling, general and administrative (SG&A) expense as a percentage of revenues.  As discussed below, during the first quarter of 2011, we made positive strides on all three fronts.

Three Months Ended March 31, 2011 Compared to Three Months Ended March 31, 2010

Revenues

	Three Months Ended				Quarter-over-Quarter
(In thousands, except percentages)	March 31, 2011		March 31, 2010		$ Change		% Change
Revenues:
Laboratory Services
Drugs-of-abuse testing  services	$	9,640	$	8,796	$	844		10%
Clinical & other laboratory services		7,975		6,890		1,085		16%
Clinical trial services		2,536		833		1,703		204%
Product Sales		5,585		4,642		943		20%
	$	25,736	$	21,161	$	4,575		22%

Our Laboratory Services segment includes revenues from drugs-of-abuse testing services, clinical & other laboratory services and clinical trial services.  Our revenues from drugs-of-abuse testing increased 10% to $9.6 million in the first quarter of 2011 due to strong revenue from new clients. Pricing for our workplace drugs-of-abuse testing services tends to be fairly stable overall; however, the average price per testing specimen can vary slightly from quarter-to-quarter.  Test price can vary by client based on the percentage of samples that test positive for drugs-of-abuse and the average number of samples per shipment.

- 15 -

Revenues in our clinical and other laboratory services increased 16% to $8.0 million in the first quarter of 2011 due to continued strong growth generated by our expanded clinical laboratory capabilities and diversification initiatives.

Revenues in clinical trial services increased 204% to $2.5 million in the first quarter of 2011 andcontinued the solid performance shown in the previous three quarters.  In the first quarter of 2010, revenues in clinical trial services were impacted by a slow-down of projects and deferral of work into future quarters.  Revenues from clinical trial services can fluctuate from quarter-to-quarter based on the project nature, size, and the actual timing of clinical trials.

Our Product Sales segment includes revenues from point-of-collection on site testing products (POCT), contract manufacturing services and other diagnostic products.

Sales of POCT products, which consist of the PROFILE®-II, PROFILE®-II A, PROFILE-II ER®, PROFILE®-III ER, PROFILE®-III, PROFILE®-III A, PROFILE®-IV, PROFILE®-V, VERDICT®-II and SURE-SCREEN® on-site test kits and other ancillary products for the detection of abused substances, increased 18% to $4.9 million in the first quarter of 2011.  The increase was due primarily to increased sales of Profile®-V sold into the hospital market with our MEDTOXScan® Reader, increased sales into the government market with our SURE-SCREEN® devices, as well as improved sales in the workplace drugs-of-abuse market with our PROFILE®-II A and PROFILE®-III A products.  Overall, pricing for our POCT devices was slightly lower than the prior year period.

Cost of Revenues and Gross Margin

	Three Months Ended										Quarter-over-Quarter
	March 31, 2011		% of Revenues			March 31, 2010		% of Revenues			$ Change		% Change
Cost of Revenues:
Cost of Services	$	12,952		64.3	%*	$	11,033		66.8	%*	$	1,919		17%
Cost of Sales		2,333		41.8	%**		2,028		43.7	%**		305		15%
	$	15,285		59.4	%	$	13,061		61.7	%	$	2,224		17%

*      Cost of services as a percentage of Laboratory Services revenues

**    Cost of sales as a percentage of Product Sales revenues

Consolidated gross margin increased to 40.6% of revenues in the first quarter of 2011, compared to 38.3% of revenues for the same period in 2010.

Laboratory Services gross margin was 35.7% in the first quarter of 2011, up from 33.2% in the first quarter of 2010.  The increase in gross margin was due to a change in test mix and an increase in volume.   Gross margin from Product Sales increased to 58.2% in the first quarter of 2011, up from 56.3% in the same period of 2010.  The increased margin is primarily due to sales mix of POCT devices, with an increase in our higher margin PROFILE®-V devices sold into the hospital market.

- 16 -

Operating Expenses

	Three Months Ended										Quarter-over-Quarter
	March 31, 2011		% of Revenues			March 31, 2010		% of Revenues			$ Change		% Change
Operating Expenses:
Selling, general and    administrative	$	8,624		33.5	%	$	7,433		35.1	%	$	1,191		16%
Research and    development		594		2.3	%		549		2.6	%		45		8%
	$	9,218		35.8	%	$	7,982		37.7	%	$	1,236		16%

Selling, General and Administrative Expenses.  Selling, general and administrative (SG&A) expenses increased to $8.6 million, or 33.5% of revenues in the first quarter of 2011, compared to $7.4 million, or 35.1% of revenues in the first quarter of 2010.  The increase was due to increased costs associated with the growth in clinical revenue and increased incentive-based compensation.  Increased expenses associated with the growth in our clinical & other laboratory services business include an increase in bad debt and billing expenses related to increased third party and patient billing.  Our sales, general and administrative expense of $8.6 million compared more closely to the previous two quarters ended December 31, 2010 and September 30, 2010, where SG&A expenses were $8.6 million and $8.4 million, respectively.

Research and Development Expenses.  Research and development expenses increased 8% to $594,000 in the first quarter of 2011, primarily due to increased spending for on-going projects in our Product Sales segment.

Liquidity and Capital Resources

Our working capital requirements have been funded primarily by various combinations of profitable operations and cash received from our revolving credit facility.  Cash and cash equivalents at March 31, 2011 were $1.0 million, compared to $1.3 million at December 31, 2010.

Net cash provided by operating activities was $1.3 million for the three months ended March 31, 2011 compared to $0.9 million for the same period of 2010.  The increase in the first quarter of 2011 was attributable to an increase in net earnings, excluding non-cash charges such as depreciation and amortization, deferred compensation, deferred income taxes and provision for losses on accounts receivable.

Net cash used in investing activities, consisting of capital expenditures, was $1.1 million for the three months ended March 31, 2011 compared to $1.0 million for the same period of 2010.  In both periods, these expenditures included equipment purchased and costs incurred to upgrade equipment, improve efficiencies and increase service levels to our clients.

Net cash used in financing activities was $0.4 million for the three months ended March 31, 2011 compared to net cash provided by financing activities of $0.4 million in the prior year period.  The change was primarily due to the repurchase of 88,975 shares of our common stock in the open market for $1.4 million in the first quarter of 2011 which were placed in trust to fund our Long-Term Incentive Plan, partially offset by net proceeds from our line of credit of $1.0 million.  In the first quarter of 2010, we received proceeds from the exercise of stock options of $0.6 million.

- 17 -

We are a party to a credit security agreement (the "Wells Fargo Credit Agreement") with Wells Fargo Bank, National Association (the “Bank”) which expires on August 31, 2011.  The Wells Fargo Credit Agreement, as amended, consists of a revolving line of credit ("Line of Credit") of up to $12.0 million bearing interest at a fluctuating rate of 2.25% above the daily three month LIBOR, as defined and calculated by the Bank.

Subject to certain conditions, the Wells Fargo Credit Agreement also provides for the issuance of letters of credit which, if drawn upon, would be deemed advances under the Line of Credit.  We are required to pay a fee equal to 0.25% per annum on the average daily unused amount of the Line of Credit.  We have granted the Bank a first priority security interest in all of the Company’s accounts receivable, other rights to payment, general intangibles, inventory, and equipment to secure all indebtedness of the Company to the Bank.

Extensions of credit under the Wells Fargo Credit Agreement are subject to certain conditions.  The Wells Fargo Credit Agreement also requires us to comply with certain financial covenants, including maintaining, on a consolidated basis:

·   Tangible Net Worth not less than $35,000,000 at each month end, with “Tangible Net Worth” defined as the aggregate of total stockholders’ equity plus subordinated debt less any intangible assets.

·   Current Ratio not less than 1.45 to 1.0 at each month end, with “Current Ratio” defined as total current assets divided by total current liabilities.

·   Pre-tax profit of not less than $1,500,000 on a rolling four-quarter basis, determined as of each fiscal quarter-end.

We are relying on expected positive cash flow from operations and our Line of Credit to fund our future working capital and asset purchases.  At March 31, 2011, we had total borrowing capacity of $12.0 million on our Line of Credit, of which $3.7 million was borrowed, leaving a net availability of $8.3 million.

In the short term, we believe that the aforementioned resources will be sufficient to fund our planned operations through 2011.  While there can be no assurance that the available capital will be sufficient to fund our future operations beyond 2011, we believe that future profitable operations, as well as access to additional capital through debt or equity financings, will be the primary means for funding our operations for the long term.

We continue to follow a plan which includes (i) aggressively monitoring and controlling costs, (ii) increasing revenues from sales of our existing products and services, (iii) developing new products and services, as well as (iv) selectively pursuing synergistic acquisitions to increase our critical mass.  However, there can be no assurance that costs can be controlled, revenues can be increased, financing may be obtained, acquisitions successfully consummated, or that we will be profitable.

- 18 -

Off-Balance Sheet Transactions

The Company does not maintain any off-balance sheet transactions, arrangements, obligations or other relationships with unconsolidated entities or others that are reasonably likely to have a material current or future effect on the Company’s financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures or capital resources.

Impact of Inflation and Changing Prices

The impact of inflation and changing prices on the Company has been primarily limited to salary, laboratory and operating supplies, fuel charges and rent increases and has historically not been material to the Company’s operations.  In the future, the Company may not be able to increase the prices of laboratory testing by an amount sufficient to cover the cost of inflation, although the Company is responding to these concerns by refocusing the laboratory operations towards higher margin testing (including clinical and pharmaceutical trials) as well as emphasizing the marketing, sales and operations of the Product Sales business.

Seasonality

The Company believes that the laboratory testing business is subject to seasonal fluctuations in pre-employment screening.  These seasonal fluctuations include reduced volume in the year-end holiday periods and other major holidays.  In addition, inclement weather may have a negative impact on volume thereby reducing net revenues and cash flows.

- 19 -

Item 3:  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

There have been no material changes in our market risk during the quarter ended March 31, 2011.  For additional information refer to Item 7A of our Annual Report on Form 10-K for the year ended December 31, 2010.

Item 4:  CONTROLS AND PROCEDURES.

Evaluation of Disclosure Controls Procedures

As of the end of the period covered by this report, we conducted an evaluation under the supervision and with the participation of our management, including our Chief Executive Officer and Chief Financial Officer, regarding the effectiveness of the design and operation of our disclosure controls and procedures pursuant to Rules 13a-15(b) and 15d-15(b) of the Securities Exchange Act of 1934 (the “Exchange Act”). Based upon that evaluation, the Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures are effective to ensure that information that is required to be disclosed by us in reports that we file under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms.

Changes in Internal Controls

There were no changes in our internal control over financial reporting that occurred during the period covered by this report that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

- 20 -

PART II                      OTHER INFORMATION

ITEM 1A                     RISK FACTORS.  There have been no material changes to our risk factors during the quarter ended March 31, 2011.  For additional information refer to Item 1A of our Annual Report on Form 10-K for the year ended December 31, 2010

ITEM 2                      UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS.

Issuer Purchases of Equity Securities

The following table provides information with respect to purchases made by us of shares of our common stock during the first quarter of 2011.

Period	Total Number of Shares Purchased (a)		Average Price Paid per Share		Total Number of Shares Purchased as part of Publicly Announced Plans or Programs (b)		Maximum Number of Shares that May Yet Be Purchased Under the Plans or Programs (b)
January 1 - 31		-		-		-		-
February 1 - 28		42,283	$	15.19		-		-
March 1 - 31		46,692		15.96		-		-
Total		88,975	$	15.60		-		-

(a)  Represents the number of shares of common stock repurchased to fund our Long-Term Incentive Plan.  Repurchases of shares may be made through open market or privately negotiated transactions at times and in such amounts as management deems appropriate.

ITEM 5 OTHER INFORMATION.

Executive Salaries for 2011

On February 11, 2011, the Compensation Committee of the Board of Directors of the Company (the “Committee”) approved 2011 base salaries for the executive officers, effective April 1, 2011, as set forth below:

Executive Officer	Title	Salary
Richard J. Braun	President and Chief Executive Officer	$	390,000
Kevin J. Wiersma	Vice President, Chief Administrative Officer, and Chief Financial Officer of MEDTOX Scientific, Inc. and Chief Operating Officer – Forensic Laboratory Operations	$	235,800
James A. Schoonover	Vice President and Chief Marketing Officer	$	235,800
B. Mitchell Owens	Vice President and Chief Operating Officer of MEDTOX Diagnostics, Inc.	$	235,800
Susan E. Puskas	Vice President, Quality Assurance,  Regulatory Affairs, and Chief Operating Officer – Clinical  Laboratory Operations	$	235,800

- 21 -

Target Financial Objectives for Fiscal Year 2011 under the Annual Incentive Plan and Long Term Incentive Plan

On February 21, 2011, the Committee approved weighted target financial objectives for the Company’s 2011 Annual Incentive Plan and Long-Term Incentive Plan (LTIP). Awards will be based on the target payouts set forth below, which are expressed as a percentage of base salary. Specific payments to individuals could exceed the following targets if the Company achieves more than 100% of its target financial objectives, but in no event will the Annual Incentive Payment or LTIP individually exceed two times base salary.

Title	Target Payout %
Chief Executive Officer	100%
Chief Financial Officer and Chief Operating Officer of MEDTOX Laboratories, Inc.	60%
Vice President and Chief Marketing Officer	60%
Vice President and Chief Operating Officer of MEDTOX Diagnostics, Inc.	60%
Vice President Quality, Regulatory Affairs, and Human Resources	60%

Employees must be employed by the Company as of December 31, 2011, and at the time of the awards in order to participate in the Plans, and awards may be adjusted on a pro rata basis to the extent any employee is employed for only a portion of the year 2011. The Chief Executive Officer will recommend individual awards for all participating employees (except for the Chief Executive Officer) for approval by the Committee based on an assessment of each individual’s performance. The Committee may approve or disapprove any recommended awards in whole or in part in its sole discretion. The Committee shall determine the award for the Chief Executive Officer based on an assessment of his performance for 2011.

ITEM 6 EXHIBITS.  See Exhibit Index on page following signature page

- 22 -

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

Signature	Title	Date
/s/ Richard J. Braun	President, Chief Executive Officer, and	April 28, 2011
Richard J. Braun	Chairman of the Board of Directors (Principal Executive Officer)
/s/ Kevin J. Wiersma	Vice President and Chief Financial Officer	April 28, 2011
Kevin J. Wiersma	(Principal Financial Officer)
/s/ Angela M. Lacis	Corporate Controller	April 28, 2011
Angela M. Lacis	(Principal Accounting Officer)

- 23 -

EXHIBIT INDEX

MEDTOX SCIENTIFIC, INC.

FORM 10-Q FOR QUARTER ENDED MARCH 31, 2011

Exhibit

Number                   Description

10.1 Executive Salaries for 2011.**

10.2 Target Financial Objectives for Fiscal Year 2011 under the Annual Incentive Plan and Long Term Incentive Plan.**

31.1   Certification

31.2   Certification

32.1 Section 906 Certification of Chief Executive Officer pursuant to the Sarbanes-Oxley Act of 2002.

32.2 Section 906 Certification of Chief Financial Officer pursuant to the Sarbanes-Oxley Act of 2002.

 ** Denotes a management contract or compensatory plan or arrangement

- 24 -