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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 WFal14bznfHCevdSOcpM2x2nuRZtSMQyBjEz7KYRD+XWUTdWUiPmvOBLsmjG5Bb/
 92hSBAUOmmUVKShbjZq5Hg==

<SEC-DOCUMENT>9999999995-10-003052.txt : 20101027
<SEC-HEADER>9999999995-10-003052.hdr.sgml : 20101027
<ACCEPTANCE-DATETIME>20101027001519
ACCESSION NUMBER:		9999999995-10-003052
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20101026
DATE AS OF CHANGE:		20101027
EFFECTIVENESS DATE:		20101026

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Marina Biotech, Inc.
		CENTRAL INDEX KEY:			0000737207
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				112658569
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-169882
		FILM NUMBER:		101143414

	BUSINESS ADDRESS:	
		STREET 1:		3830 MONTE VILLA PARKWAY
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021
		BUSINESS PHONE:		4259083600

	MAIL ADDRESS:	
		STREET 1:		3830 MONTE VILLA PARKWAY
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MDRNA, Inc.
		DATE OF NAME CHANGE:	20080610

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NASTECH PHARMACEUTICAL CO INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
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<SEQUENCE>1
<FILENAME>primary_doc.xml
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    <submissionType>EFFECT</submissionType>

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    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2010-10-26</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>17:00:00</finalEffectivenessDispTime>
        <form>S-3</form>
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            <entityName>Marina Biotech, Inc.</entityName>
            <fileNumber>333-169882</fileNumber>
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