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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001209191-05-059403.txt : 20051123
<SEC-HEADER>0001209191-05-059403.hdr.sgml : 20051123
<ACCEPTANCE-DATETIME>20051123113850
ACCESSION NUMBER:		0001209191-05-059403
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051122
FILED AS OF DATE:		20051123
DATE AS OF CHANGE:		20051123

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			WORMUTH DAVID E
		CENTRAL INDEX KEY:			0001251780

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-13789
		FILM NUMBER:		051223561

	MAIL ADDRESS:	
		STREET 1:		3450 MONTE VILLA PARKWAY
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NASTECH PHARMACEUTICAL CO INC
		CENTRAL INDEX KEY:			0000737207
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				112658569
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3450 MONTE VILLA PARKWAY
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021
		BUSINESS PHONE:		4259083600

	MAIL ADDRESS:	
		STREET 1:		3450 MONTE VILLA PARKWAY
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-11-22</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000737207</issuerCik>
        <issuerName>NASTECH PHARMACEUTICAL CO INC</issuerName>
        <issuerTradingSymbol>NSTK</issuerTradingSymbol>
    </issuer>

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            <rptOwnerName>WORMUTH DAVID E</rptOwnerName>
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            <rptOwnerStreet1>3450 MONTE VILLA PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BOTHELL</rptOwnerCity>
            <rptOwnerState>WA</rptOwnerState>
            <rptOwnerZipCode>98021</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Sr VP, Operations &amp; Mfg</officerTitle>
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    </reportingOwner>

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                <sharesOwnedFollowingTransaction>
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                <sharesOwnedFollowingTransaction>
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    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Nastech Pharmaceutical Company Inc Stock Options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>4.625</value>
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            <transactionDate>
                <value>2005-11-22</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>X</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>4.625</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2004-03-23</value>
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            <expirationDate>
                <value>2006-03-23</value>
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            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
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            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>85000</value>
                </sharesOwnedFollowingTransaction>
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            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
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        </derivativeTransaction>
    </derivativeTable>

    <footnotes></footnotes>

    <remarks>Exercise and sale of options pursuant to 10B5-1 Trading Plan adopted July 13, 2005.</remarks>

    <ownerSignature>
        <signatureName>/s/ Philip C. Ranker



Philip C. Ranker
Attorney in Fact</signatureName>
        <signatureDate>2005-11-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----