Condensed Consolidated Statements Of Cash Flows (USD $) In Thousands	6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010
Operating activities:
Net loss	$ (7,250)	$ (13,591)
Adjustments to reconcile net loss to net cash used in operating activities:
Compensation related to restricted stock, stock options and employee stock purchase plan	572	905
Depreciation and amortization	704	828
Non-cash research and development expense	30	0
Non-cash amortization of discount on notes payable and debt issuance costs	0	1,277
Non-cash restructuring expense	225	232
Accretion of restructuring liability	61	54
Change in fair value of price adjustable warrants and subscription investment units	(3,466)	115
Changes in assets and liabilities:
Accounts receivable	54	101
Prepaid expenses and other assets	260	200
Accounts payable	(598)	620
Deferred revenue	476	67
Accrued expenses and deferred rent and other liabilities	(345)	253
Accrued restructuring	(153)	0
Net cash used in operating activities	(9,430)	(8,939)
Investing activities:
Change in restricted cash	(140)	(159)
Purchases of property and equipment	0	(158)
Net cash used in investing activities	(140)	(317)
Financing activities:
Proceeds from sales of common shares and warrants, net	10,726	4,943
Proceeds from exercise of warrants, subscription investment units, stock options and employee stock purchase plan purchases	2,483	2,639
Borrowings on note payable	0	3,000
Payments on note payable	0	(1,000)
Net cash provided by financing activities	13,209	9,582
Net increase in cash	3,639	326
Cash - beginning of year	1,066	748
Cash - end of period	4,705	1,074
Non-cash financing activities:
Issuance of common stock to settle liabilities	80	55
Supplemental disclosure:
Cash paid for interest	$ 0	$ 10