Stock Incentive Plans (Tables)

9 Months Ended

Sep. 30, 2012

Stock Incentive Plans [Abstract]

Schedule of Stock-Based Compensation Expense

Stock-based Compensation - The following table summarizes stock-based compensation expense (in thousands):

	Three Months ended September 30,					Nine months ended September 30,
	2011		2012			2011		2012
Stock-based compensation:
Research and development	$	103	$	34		$	295	$	186
Selling, general and administrative		13		(33	)		393		159
Total stock-based compensation	$	116	$	1		$	688	$	345

Schedule of Stock Option Activity

The following table summarizes stock option activity during the nine months ended September 30, 2012:

	Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life		Aggregate Intrinsic Value
								(in thousands)
Outstanding December 31, 2011		578,257		$	26.22
Options expired		(15,446	)		60.43
Options forfeited		(204,438	)		2.27
Outstanding at September 30, 2012		358,373		$	38.41		5.9 years	$	-
Exercisable at September 30, 2012		254,860		$	52.71		4.6 years	$	-