Condensed Consolidated Statement of Stockholders' Equity (USD $) In Thousands, except Share data	Total	Common Stock and Additional Paid-In Capital [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2011	$ 38	$ 320,232	$ (320,194)
Balance, shares at Dec. 31, 2011	10,438,912	10,438,912
Proceeds from the issuance of common shares and warrants, net	1,111	1,111
Proceeds from the issuance of common shares and warrants, net, shares		1,600,002
Shares issued in connection with license agreement	107	107
Shares issued in connection with license agreement, shares		112,385
Fractional shares redeemed, shares		(104)
Proceeds from employee stock purchase plan purchases	2	2
Proceeds from employee stock purchase plan purchases, shares		3,908
Compensation related to stock options and employee stock purchase plan, net of forfeitures	229	229
Net loss	(4,824)		(4,824)
Balance at Mar. 31, 2012	$ (3,337)	$ 321,681	$ (325,018)
Balance, shares at Mar. 31, 2012	12,155,103	12,155,103