Exhibit 1

JOINT FILING AGREEMENT OF

AMPERSAND 2006 LIMITED PARTNERSHIP

AMP-06 MANAGEMENT COMPANY LIMITED PARTNERSHIP AND

AMP-06 MC LLC

           The undersigned persons agree and consent pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, as of the date set forth below, to the joint filing on their behalf of the Schedule 13D to which this Exhibit is attached, in connection with their beneficial ownership of the common stock of Marina Biotech, Inc. at July 21, 2010 and agree that such statement is filed on behalf of each of them.

	AMPERSAND 2006 LIMITED PARTNERSHIP
	By: AMP-06 Management Company Limited Partnership, its General Partner
Dated:  August 2, 2010		/s/ Richard A. Charpie
	By: Richard A. Charpie, Principal Managing Member

	AMP-06 MANAGEMENT COMPANY LIMITED PARTNERSHIP
	By: AMP-06 MC LLC, its General Partner
Dated:  August 2, 2010		/s/ Richard A. Charpie
	By: Richard A. Charpie, Principal Managing Member

	AMP-06 MC, LLC
Dated:  August 2, 2010		/s/ Richard A. Charpie
	By: Richard A. Charpie, Principal Managing Member