NPORT-EX 2 vg_healthcarefund.htm
Vanguard® Health Care Fund
Schedule of Investments (unaudited)
As of April 30, 2024
The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at www.sec.gov.
    Shares Market
Value
($000)
Common Stocks (98.2%)
Belgium (3.4%)
  UCB SA 7,592,598 1,006,855
* Argenx SE 1,367,795 510,959
* Galapagos NV 1,175,458 33,248
      1,551,062
Brazil (0.0%)
*,1 Hapvida Participacoes e Investimentos SA 8,909,471 6,331
China (0.5%)
* Legend Biotech Corp. ADR 1,900,644 83,134
  Shandong Weigao Group Medical Polymer Co. Ltd. Class H 77,092,000 52,280
*,2 Zai Lab Ltd. ADR 2,814,054 44,462
* Zai Lab Ltd. 16,916,600 27,190
  WuXi AppTec Co. Ltd. Class A 2,206,900 13,261
*,1 Wuxi Biologics Cayman Inc. 5,232,700 9,065
      229,392
Denmark (4.3%)
  Novo Nordisk A/S Class B 8,412,411 1,078,826
* Genmab A/S 2,088,852 579,928
*,2 Ascendis Pharma A/S ADR 1,822,681 252,332
* Genmab A/S ADR 2,285,855 63,295
      1,974,381
Italy (0.2%)
  DiaSorin SpA 552,359 55,787
  Stevanato Group SpA 1,642,580 46,058
      101,845
Japan (7.2%)
  Daiichi Sankyo Co. Ltd. 40,320,290 1,357,088
3 Eisai Co. Ltd. 19,123,817 785,396
  Chugai Pharmaceutical Co. Ltd. 16,783,700 533,786
  Otsuka Holdings Co. Ltd. 7,660,100 327,522
  Terumo Corp. 13,952,800 236,697
  Astellas Pharma Inc. 6,551,900 62,884
      3,303,373
Switzerland (4.7%)
  Novartis AG (Registered) 17,040,665 1,653,924
  Alcon Inc. 2,660,263 203,981
* Galderma Group AG 2,730,442 203,465
  Tecan Group AG (Registered) 236,453 83,417
      2,144,787
United Kingdom (8.1%)
  AstraZeneca plc 18,232,979 2,757,717

    Shares Market
Value
($000)
  GSK plc 31,901,977 661,868
*,3 Immunocore Holdings plc ADR 2,897,598 171,190
1 ConvaTec Group plc 15,436,613 48,028
  Genus plc 1,791,160 40,281
* Autolus Therapeutics plc ADR 7,298,865 26,860
*,2 Verona Pharma plc ADR 917,405 14,174
      3,720,118
United States (69.8%)
  Eli Lilly & Co. 5,329,601 4,162,951
  UnitedHealth Group Inc. 6,293,482 3,044,157
  Merck & Co. Inc. 19,233,777 2,485,389
  Danaher Corp. 5,113,563 1,261,107
  Thermo Fisher Scientific Inc. 2,108,134 1,198,938
  Pfizer Inc. 45,023,705 1,153,507
  Elevance Health Inc. 2,136,085 1,129,092
* Boston Scientific Corp. 13,757,254 988,734
* Biogen Inc. 4,558,453 979,247
  Abbott Laboratories 7,755,740 821,876
  HCA Healthcare Inc. 2,648,543 820,572
  Zoetis Inc. 5,091,415 810,757
* Alnylam Pharmaceuticals Inc. 5,543,308 797,959
* Edwards Lifesciences Corp. 9,402,342 796,096
* Vertex Pharmaceuticals Inc. 1,802,778 708,149
  Humana Inc. 2,264,092 683,959
  Stryker Corp. 2,022,549 680,588
* Centene Corp. 8,607,919 628,895
* Intuitive Surgical Inc. 1,675,518 620,980
* Regeneron Pharmaceuticals Inc. 675,638 601,764
* Moderna Inc. 4,616,422 509,237
  Agilent Technologies Inc. 3,253,141 445,810
*,3 Apellis Pharmaceuticals Inc. 9,503,375 419,954
  Cencora Inc. 1,641,246 392,340
* IQVIA Holdings Inc. 1,600,147 370,866
* Molina Healthcare Inc. 849,274 290,537
  Laboratory Corp. of America Holdings 1,381,908 278,275
* Acadia Healthcare Co. Inc. 3,658,046 270,476
* Insulet Corp. 1,457,112 250,536
* REVOLUTION Medicines Inc. 6,540,577 243,833
* Sarepta Therapeutics Inc. 1,914,236 242,457
*,3 Alkermes plc 8,601,892 211,090
* Waters Corp. 666,877 206,092
* United Therapeutics Corp. 842,593 197,445
* Blueprint Medicines Corp. 2,149,647 196,349
*,3 agilon health Inc. 34,720,760 190,964
  Encompass Health Corp. 2,095,873 174,754
* Vaxcyte Inc. 2,633,933 159,485
* Align Technology Inc. 561,631 158,593
* Exact Sciences Corp. 2,657,237 157,707
* Ionis Pharmaceuticals Inc. 3,591,680 148,193
  Teleflex Inc. 682,126 142,394
* Amicus Therapeutics Inc. 13,772,376 137,586
*,3 Celldex Therapeutics Inc. 3,369,316 126,080
* Option Care Health Inc. 4,107,073 122,760
*,3 Denali Therapeutics Inc. 7,674,724 118,498
*,3 Structure Therapeutics Inc. ADR 2,953,015 116,467
* PTC Therapeutics Inc. 3,393,863 109,113
*,3 Rocket Pharmaceuticals Inc. 4,913,120 105,730
* Xenon Pharmaceuticals Inc. 2,542,337 103,346

    Shares Market
Value
($000)
* Evolent Health Inc. Class A 3,351,619 92,974
* Cytokinetics Inc. 1,469,555 90,113
* Surgery Partners Inc. 3,609,838 90,065
*,3 Syndax Pharmaceuticals Inc. 4,249,352 89,789
* Intellia Therapeutics Inc. 3,296,787 70,551
* Privia Health Group Inc. 3,229,900 59,430
* Apogee Therapeutics Inc. 1,135,110 57,096
* Morphic Holding Inc. 1,927,084 52,552
* Prothena Corp. plc 2,394,263 48,699
* Kymera Therapeutics Inc. 1,446,764 48,640
* PACS Group Inc. 1,910,494 47,705
* Qiagen NV 1,086,762 46,003
* TG Therapeutics Inc. 3,066,304 41,886
* Sage Therapeutics Inc. 2,859,637 39,863
* Akero Therapeutics Inc. 1,543,035 30,691
      31,877,741
Total Common Stocks (Cost $27,262,641) 44,909,030
Temporary Cash Investments (1.5%)
Money Market Fund (0.0%)
4,5 Vanguard Market Liquidity Fund, 5.394% 43,433 4,343
    Face
Amount
($000)
 
Repurchase Agreements (1.5%)
  Bank of America Securities LLC, 5.320%, 5/1/24
(Dated 4/30/24, Repurchase Value $19,003,000, collateralized by Fannie Mae 3.500%–5.773%, 6/1/30–4/1/49, Freddie Mac 3.000%–6.020%, 9/1/37–4/1/54, and Ginnie Mae 4.470%, 2/15/65, with a value of $19,380,000) 
19,000 19,000
  Bank of Nova Scotia, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $73,011,000, collateralized by U.S. Treasury Bill 0.000% 6/6/24–8/20/24, and U.S. Treasury Note/Bond 0.250%–4.625%, 6/30/24–5/15/51, with a value of $74,471,000) 
73,000 73,000
  Barclays Capital Inc., 5.300%, 5/1/24
(Dated 4/30/24, Repurchase Value $75,511,000, collateralized by U.S. Treasury Note/Bond 1.250%, 6/30/28, with a value of $77,010,000)
75,500 75,500
  BNP Paribas Securities Corp., 5.300%, 5/1/24
(Dated 4/30/24, Repurchase Value $76,411,000, collateralized by U.S. Treasury Bill 0.000%, 5/23/24, U.S. Treasury Inflation Indexed Note/Bond 5.526%, 1/31/25, and U.S. Treasury Note/Bond 1.375%–3.500%, 7/15/25–8/15/52, with a value of $77,928,000) 
76,400 76,400
  BNP Paribas Securities Corp., 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $61,009,000, collateralized by Fannie Mae 1.820%–7.025%, 12/1/30–2/1/54, and Freddie Mac 1.220%–6.500%, 11/1/32–10/1/53, with a value of $62,220,000) 
61,000 61,000
  Credit Agricole Securities, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $21,403,000, collateralized by U.S. Treasury Inflation Indexed Note/Bond 2.375%, 10/15/28, with a value of $21,828,000)
21,400 21,400
  HSBC Bank USA, 5.300%, 5/1/24
(Dated 4/30/24, Repurchase Value $29,804,000, collateralized by U.S. Treasury Inflation Indexed Note/Bond 0.125%–1.000%, 1/15/30–2/15/46, with a value of $30,396,000)
29,800 29,800
  HSBC Bank USA, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $44,507,000, collateralized by Fannie Mae 1.500%–6.500%, 9/1/29–12/1/53, with a value of $45,390,000)
44,500 44,500

    Face
Amount
($000)
Market
Value
($000)
  JP Morgan Securities LLC, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $40,006,000, collateralized by U.S. Treasury Note/Bond 1.500%, 1/31/27, with a value of $40,800,000)
40,000 40,000
  Natixis SA, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $116,417,000, collateralized by Federal Home Loan Bank 4.000%–4.080%, 10/24/29–5/25/33, Freddie Mac 2.150%–2.700%, 12/28/37–7/13/40, U.S. Treasury Inflation Indexed Note/Bond 0.125%– 1.500%, 7/15/26–2/15/53 and U.S. Treasury Note/Bond 0.500%–4.750%, 4/30/27–11/15/53, with a value of $118,728,000) 
116,400 116,400
  Nomura International plc, 5.310%, 5/1/24
(Dated 4/30/24, Repurchase Value $76,711,000, collateralized by U.S. Treasury Bill 0.000%, 6/20/24, U.S. Treasury Inflation Indexed Note/Bond 0.125%, 7/15/24, and U.S. Treasury Note/Bond 2.375%–2.500%, 8/15/24–1/31/25, with a value of $78,312,000) 
76,700 76,700
  RBC Capital Markets LLC, 5.300%, 5/1/24
(Dated 4/30/24, Repurchase Value $30,104,000, collateralized by Freddie Mac 3.500%–4.000%, 5/1/47–3/1/53, and U.S. Treasury Bill 0.000%, 10/17/24, with a value of $30,702,000)
30,100 30,100
      663,800
Total Temporary Cash Investments (Cost $668,142) 668,143
Total Investments (99.7%) (Cost $27,930,783) 45,577,173
Other Assets and Liabilities—Net (0.3%) 128,477
Net Assets (100%) 45,705,650
Cost is in $000.
* Non-income-producing security.
1 Security exempt from registration under Rule 144A of the Securities Act of 1933. Such securities may be sold in transactions exempt from registration, normally to qualified institutional buyers. At April 30, 2024, the aggregate value was $63,424,000, representing 0.1% of net assets.
2 Includes partial security positions on loan to broker-dealers. The total value of securities on loan is $4,044,000.
3 Considered an affiliated company of the fund as the fund owns more than 5% of the outstanding voting securities of such company.
4 Affiliated money market fund available only to Vanguard funds and certain trusts and accounts managed by Vanguard. Rate shown is the 7-day yield.
5 Collateral of $4,253,000 was received for securities on loan.
  ADR—American Depositary Receipt.
A. Security Valuation: Securities are valued as of the close of trading on the New York Stock Exchange (generally 4 p.m., Eastern time) on the valuation date. Equity securities are valued at the latest quoted sales prices or official closing prices taken from the primary market in which each security trades; such securities not traded on the valuation date are valued at the mean of the latest quoted bid and asked prices. Securities for which market quotations are not readily available, or whose values have been affected by events occurring before the fund’s pricing time but after the close of the securities’ primary markets, are valued by methods deemed by the valuation designee to represent fair value and subject to oversight by the board of trustees. These procedures include obtaining quotations from an independent pricing service, monitoring news to identify significant market- or security-specific events, and evaluating changes in the values of foreign market proxies (for example, ADRs, futures contracts, or exchange-traded funds), between the time the foreign markets close and the fund’s pricing time. When fair-value pricing is employed, the prices of securities used by a fund to calculate its net asset value may differ from quoted or published prices for the same securities. Investments in Vanguard Market Liquidity Fund are valued at that fund's net asset value. Other temporary cash investments are valued using the latest bid prices or using valuations based on a matrix system (which considers such factors as security prices, yields, maturities, and ratings), both as furnished by independent pricing services.

B. Foreign Currency: Securities and other assets and liabilities denominated in foreign currencies are translated into U.S. dollars using exchange rates obtained from an independent third party as of the fund’s pricing time on the valuation date. Realized gains (losses) and unrealized appreciation (depreciation) on investment securities include the effects of changes in exchange rates since the securities were purchased, combined with the effects of changes in security prices. Fluctuations in the value of other assets and liabilities resulting from changes in exchange rates are recorded as unrealized foreign currency gains (losses) until the assets or liabilities are settled in cash, at which time they are recorded as realized foreign currency gains (losses).
C. Repurchase Agreements: The fund enters into repurchase agreements with institutional counterparties. Securities pledged as collateral to the fund under repurchase agreements are held by a custodian bank until the agreements mature, and in the absence of a default, such collateral cannot be repledged, resold, or rehypothecated. Each agreement requires that the market value of the collateral be sufficient to cover payments of interest and principal. The fund further mitigates its counterparty risk by entering into repurchase agreements only with a diverse group of prequalified counterparties, monitoring their financial strength, and entering into master repurchase agreements with its counterparties. The master repurchase agreements provide that, in the event of a counterparty's default (including bankruptcy), the fund may terminate any repurchase agreements with that counterparty, determine the net amount owed, and sell or retain the collateral up to the net amount owed to the fund. Such action may be subject to legal proceedings, which may delay or limit the disposition of collateral.
D.  Various inputs may be used to determine the value of the fund’s investments. These inputs are summarized in three broad levels for financial statement purposes. The inputs or methodologies used to value securities are not necessarily an indication of the risk associated with investing in those securities.
Level 1—Quoted prices in active markets for identical securities.
Level 2—Other significant observable inputs (including quoted prices for similar securities, interest rates, prepayment speeds, credit risk, etc.).
Level 3—Significant unobservable inputs (including the fund’s own assumptions used to determine the fair value of investments). Any investments valued with significant unobservable inputs are noted on the Schedule of Investments.
The following table summarizes the market value of the fund’s investments as of April 30, 2024, based on the inputs used to value them:
  Level 1
($000)
Level 2
($000)
Level 3
($000)
Total
($000)
Investments        
Assets        
Common Stocks—North and South America 31,884,072 31,884,072
Common Stocks—Other 904,970 12,119,988 13,024,958
Temporary Cash Investments 4,343 663,800 668,143
Total 32,793,385 12,783,788 45,577,173

E.  Certain of the fund’s investments are in companies that are considered to be affiliated companies of the fund because the fund owns more than 5% of the outstanding voting securities of the company or the issuer is another member of The Vanguard Group. Transactions during the period in securities of these companies were as follows:
    Current Period Transactions  
  Jan. 31,
2024
Market
Value
($000)
Purchases
at Cost
($000)
Proceeds
from
Securities
Sold
($000)
Realized
Net
Gain
(Loss)
($000)
Change in
Unrealized
App. (Dep.)
($000)
Income
($000)
Capital Gain
Distributions
Received
($000)
Apr. 30,
2024
Market
Value
($000)
agilon health Inc. 179,707 26,464 (15,207) 190,964
Alkermes plc 232,681 (21,591) 211,090
Apellis Pharmaceuticals Inc. 601,469 (181,515) 419,954
Celldex Therapeutics Inc. NA1 47,135 769 126,080
Denali Therapeutics Inc. NA1 45,779 (8,940) 118,498
Eisai Co. Ltd. 900,515 (115,119) 785,396
Immunocore Holdings plc ADR 209,467 (38,277) 171,190
Rocket Pharmaceuticals Inc. NA1 23,638 (35,472) 105,730
Sage Therapeutics Inc. 110,372 21,639 (71,495) 22,626 NA2
Structure Therapeutics Inc. ADR 105,169 25,584 (14,286) 116,467
Syndax Pharmaceuticals Inc. 87,069 2,720 89,789
Vanguard Market Liquidity Fund 14,873 NA3 NA3 (2) 4,343
Total 2,441,322 168,600 21,639 (71,497) (404,292) 2,339,501
1 Not applicable—at January 31, 2024, the issuer was not an affiliated company of the fund.
2 Not applicable—at April 30, 2024, the security was still held, but the issuer was no longer an affiliated company of the fund.
3 Not applicable—purchases and sales are for temporary cash investment purposes.