UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Notice of Effectiveness
Effectiveness Date: September 22, 2010 4:00 P.M.
Form: S-4
CIK: 0000732485
Company Name: GENZYME CORP
File Number: 333-169257
CIK: 0001495465
Company Name: Genzyme Therapeutic Products Limited Partnership
File Number: 333-169257-01