EX-21 6 a2190533zex-21.htm EXHIBIT 21
QuickLinks -- Click here to rapidly navigate through this document


EXHIBIT 21


SUBSIDIARIES OF THE REGISTRANT

Name
  Direct Parent(s)   Ownership   Jurisdiction of
Incorporation

Genzyme Europe B.V. 

  Imtix SangStat (Switzerland) GmbH     100 % The Netherlands

Genzyme Flanders BVBA

  Genzyme International Holdings Limited
Genzyme Global S.à.r.l.
    99.9
0.1
%
%
Belgium

Genzyme International Holdings Limited

  Genzyme Global S.à.r.l.     100 % Republic of Ireland

Genzyme Ireland Limited

  Genzyme International Holdings Limited     100 % Republic of Ireland

Genzyme Limited

  Genzyme Global S.à.r.l     100 % United Kingdom

Genzyme Securities Corporation

  Genzyme Therapeutic Products Limited Partnership     100 % Massachusetts, United States

Genzyme Polyclonals S.A.S. 

  SangStat Medical, LLC
SangStat Atlantique S.A.S.
    1
99
%
%
France

Genzyme Therapeutic Products Limited
Partnership

   
Genzyme Therapeutic Products Corporation
Genzyme Corporation
      
1
99

%
%
  
Massachusetts, United States

Genzyme Therapeutic Products Corporation

  Genzyme Corporation     100 % Massachusetts, United States

Imtix SangStat (Switzerland) GmbH

  Genzyme Global S.à.r.l.     100 % Switzerland

SangStat Atlantique S.A.S. 

  SangStat Medical, LLC     100 % France

Genzyme Global S.à.r.l. 

  Genzyme Luxembourg S.à.r.l.     100 % Luxembourg

Genzyme Luxembourg S.à.r.l. 

  Genzyme Corporation     100 % Luxembourg



QuickLinks

SUBSIDIARIES OF THE REGISTRANT