EXHIBIT 23.1
                  CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the incorporation by reference in this Registration
Statement on Form S-8 of Genzyme Corporation of: our report dated February
23, 2000, except for the information in Note A as to which the date is
October 11, 2000, relating to the financial statements and financial
statement schedules of Genzyme Corporation, which appears in Genzyme
Corporation's Annual Report on Form 10-K for the year ended December 31,
1999, as amended; our reports dated February 23, 2000, relating to the
financial statements and financial statement schedules of Genzyme General,
Genzyme Molecular Oncology, Genzyme Surgical Products and Genzyme Tissue
Repair, which appear in Genzyme Corporation's Annual Report on Form 10-K for
the year ended December 31, 1999, as amended; and our report dated June 23,
2000 relating to the financial statements and supplemental schedule of the
Genzyme Retirement Savings Plan, which appears in Genzyme Corporation's Form
10-K/A, as filed on June 28, 2000.

/s/ PRICEWATERHOUSECOOPERS LLP

PRICEWATERHOUSECOOPERS LLP
Boston, Massachusetts
December 14, 2000