-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, FBx3Ul5RC2zL+wKsUsLamtj92O5mKAWemgu3Lnu69qHfsN/OaB1gjBwIynCTK8j0 3kgVLqayPwtkmD6jz1KAIQ== 0000912057-00-017684.txt : 20000413 0000912057-00-017684.hdr.sgml : 20000413 ACCESSION NUMBER: 0000912057-00-017684 CONFORMED SUBMISSION TYPE: 425 PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20000412 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: GENZYME CORP CENTRAL INDEX KEY: 0000732485 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 061047163 STATE OF INCORPORATION: MA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 425 SEC ACT: SEC FILE NUMBER: 000-14680 FILM NUMBER: 599713 BUSINESS ADDRESS: STREET 1: ONE KENDALL SQ CITY: CAMBRIDGE STATE: MA ZIP: 02139 BUSINESS PHONE: 6172527500 MAIL ADDRESS: STREET 1: ONE KENDALL SQUARE CITY: CAMBRIDGE STATE: MA ZIP: 02139 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: BIOMATRIX INC CENTRAL INDEX KEY: 0000747952 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 133058261 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 425 BUSINESS ADDRESS: STREET 1: 65 RAILROAD AVE CITY: RIDGEFIELD STATE: NJ ZIP: 07657 BUSINESS PHONE: 2019459550 MAIL ADDRESS: STREET 1: 65 RAILROAD AVE STREET 2: 65 RAILROAD AVE CITY: RIDGEFIELD STATE: NJ ZIP: 07657 425 1 FORM 425 Filed by Biomatrix, Inc. (Commission File No. 001-14221) Pursuant to Rule 425 under the Securities Act of 1933 and deemed filed pursuant to Rule 14a-12 of the Securities Exchange Act of 1934 Subject Companies: Biomatrix, Inc., Genzyme Corporation (Commission File No. 000-14680) and Genzyme Corporation's Surgical Products Division and Tissue Repair Division [The following slide show presentation was first presented by Rory Riggs of Biomatrix, Inc. on April 10, 2000, at a meeting with investors at the University Club, 1 West 54th Street, New York, New York.] SLIDE: PIONEERING BioSurgery SLIDE: Creating a Powerful New Biotech Company - - High value products, early in their life cycles - - A high value pipeline resting on well-regarded scientific platforms - - Expertise and infrastructure to build a global business - - A unique and differentiating strategy SLIDE: Forward-Looking Statements - - This presentation contains forward-looking statements - - Actual results may differ materially - - Risk factors described on Form 8-K filed on June 11, 1999 SLIDE: Source of Important Information Investors are urged to read the joint proxy statement/prospectus relating to the foregoing transaction to be filed with the Securities and Exchange Commission because it will contain important information. The joint proxy statement/prospectus and other documents filed by Genzyme and Biomatrix with the Commission may be obtained, when they become available, for free at the Commission's web site (www.sec.gov). The joint proxy statement/prospectus and these other documents may also be obtained for free from Genzyme or Biomatrix, as the case may be. Requests to Genzyme should be directed to Genzyme Corporation, One Kendall Square, Building 1400, Cambridge, Massachusetts 02139, Attn: Investor Relations, (617) 252-7500, or you can access documents on its web site (www.genzyme.com). Requests to Biomatrix should be directed to Biomatrix, Inc., 65 Railroad Avenue, Ridgefield, New Jersey 07657, Attn: Investor Relations, (201) 945-9550, or you can access the documents on its web site (www.biomatrix.com). SLIDE: Overview - - Strategic vision - - Transaction structure - - Creating a new form of biotech company SLIDE: Pioneering Biosurgery: Convergence of mechanical and biological approaches /---------------------------/------------------------------/ Medical / / Pharmaceuticals / MARKETS / / Biotechnology / / Genzyme / /---------------------------/------------------------------/ Surgical / / / / Device BioSurgery / / / / /---------------------------/------------------------------/ Mechanical Biological PRODUCTS
SLIDE: Elements of Strategy - - Create a real business - - Leader in selected high growth markets - - Substantial investment in product development in targeted diseases - - Diversify risk SLIDE: Creating a Real Business - - 1,300 employees worldwide - - 6 manufacturing plants - - Access to Genzyme Corporation's 450 scientists and 180 clinical and regulatory staff - - Established US and European sales forces in orthopedics and cardiothoracic surgery - - Product sales capabilities in >70 countries SLIDE: Leader in High Growth Markets - - Orthopedic Surgery - - Cardiothoracic Surgery SLIDE: Overview - - Strategic vision - - Transaction structure - - Creating a new form of biotech SLIDE: Creating a New Enterprise: GENZYME BIOSURGERY [CHART] Genzyme Surgical Products (NASD:GZSP) Pioneer in BioSurgery [Arrow pointing to "Genzyme BioSurgery"] Genzyme Tissue Repair (NASD:GZTR) Leader in Bio-Orthopedics [Arrow pointing to "Genzyme BioSurgery"] Biomatrix (NYSE:BXM) Pioneer in viscoelastic medical products [Arrow pointing to "Genzyme BioSurgery"] [END CHART] SLIDE: Genzyme Biosurgery - - Proposed ticker (NASD:GZBX) - - 35 million shares outstanding - - Biomatrix shareholders $245M +/ - cash 47% of GZBX (Exchange 1 for 1) - - Genzyme Tissue Repair shareholders 27% of GZBX (Exchange 0.3352) - - Genzyme Surgical Products shareholders 26% of GZBX (Exchange 0.6060) SLIDE: Financial Strength - - Revenue of >$250M - - Revenue growth 30% - - Positive cash earnings per share - - >$100M cash - - Substantial market capitalization SLIDE: Overview - - Strategic vision - - Transaction structure - - Creating a new form of biotech company SLIDE: Creating a Powerful New Biotech Company - - High value products, early in their life cycles - - A high value pipeline resting on well-regarded scientific platforms - - Expertise and infrastructure to build a global business SLIDE: Bio-Orthopedics We are focused on the fundamental problems of joint disease SLIDE: Attacking Joint Disease Through...
Biotherapeutics [ with an arrow pointing to ] Biomaterials - Cell Therapy - Synvisc -Registered-Trademark - Gene Therapy - Sepra -Registered-Trademark Products - Protein Therapy - Other - Drug Discovery
SLIDE: Bio-Orthopedic Product Pipeline [CHART] RESEARCH PRECLINICAL DEVELOPMENT CLINICAL DEVELOPMENT Concept [ with an arrow pointing to ] Market OA5025 TGF-[BETA] Bondek ORS [Arrow pointing to "Research" portion of Concept to Market Arrow] Tissue Welding Carticel II Sepra -Registered-Trademark ORS Synvisc -Registered-Trademark Plus [Arrow pointing to "Preclinical Development" portion of Concept to Market Arrow] Hylagel Nuro Quick Tack Synvisc -Registered-Trademark: other joints [Arrow pointing to "Clinical Development" portion of Concept to Market Arrow] Synvisc -Registered-Trademark Carticel -Registered-Trademark Orthevac -Registered-Trademark Tevdek -Registered-Trademark [Arrow pointing to "Market" portion of Concept to Market Arrow] [END CHART] SLIDE: Bio-Orthopedic Strengths - - > $100M in revenue growing > 30% - - Two direct sales forces plus five pharma distribution partners worldwide - - Expanding high value pipeline SLIDE: Bio-Cardiothoracic We are focused on serious heart and lung disease [Picture showing heart operation] SLIDE: Attacking Serious Heart Disease Through... [Chart] Biotherapeutics [Arrow pointing to "Biomaterials"] - - Gene Therapy - - Cell Therapy - - Protein Therapy - - Drug Discovery Biomaterials [Arrow pointing to "Devices"] - - Sepra -Registered-Trademark Products - - FocalSeal -Registered-Trademark-L - - Other Devices - - Chest Drains - - Instruments - - Sutures - - Minimally Invasive Instruments [End Chart] SLIDE: Genzyme Cardiothoracic Product Pipeline [CHART] RESEARCH PRECLINICAL DEVELOPMENT CLINICAL DEVELOPMENT Concept [ with an arrow pointing to ] Market Surface modification [Arrow pointing to "RESEARCH" portion of Concept to Market Arrow] Cell Therapy (Ventricular Aneurysm) [Arrow pointing to "RESEARCH" portion of Concept to Market Arrow] Drug Delivery - Atrial Fibrillation - Local, Sustained Anesthetic Gene Therapy - CHF - Restenosis Cell Therapy [Arrow pointing to "PRECLINICAL DEVELOPMENT" portion of Concept to Market Arrow] Sepra Coat -Registered-Trademark - Atrial Fibrillation [Arrow pointing to "PRECLINICAL DEVELOPMENT" portion of Concept to Market Arrow] Gene Therapy - Angiogenesis [Arrow pointing to "PRECLINICAL DEVELOPMENT" portion of Concept to Market Arrow] Seprafilm-TM-II - Adhesions [Arrow pointing to "CLINICAL DEVELOPMENT" portion of Concept to Market Arrow] FocalSeal -Registered-Trademark-L [Arrow pointing to "CLINICAL DEVELOPMENT" portion of Concept to Market Arrow] MISCV Sepra Film -Registered-Trademark [Arrow pointing to portion of Concept to Market Arrow between "CLINICAL DEVELOPMENT" and "Market"] [END CHART] SLIDE: Bio-Cardio Strengths - - > $90 million in revenue growing 20% - - Well established brands - - Well respected direct sales force augmented by strong distribution worldwide - - High value pipeline SLIDE: Genzyme Biosurgery A Leader in Adhesion Prevention New Formulations - - Sepra Film -Registered-Trademark - - Sepragel -Registered-Trademark - - Sepramesh-TM- - - Sepra Coat -Registered-Trademark - - Hylasine -Registered-Trademark - - Hylagel -Registered-Trademark Nuro New Anti-Adhesion Applications - - Hernia repair - - Cardiovascular surgery - - Sinus surgery - - Laparoscopic surgery - - Orthopedics SLIDE: High Growth Early Life Cycle Products - - Bio-Orthopedic - Synvisc -Registered-Trademark - Carticel -Registered-Trademark - - Cardiothoracic - Beating heart CABG instruments - FocalSeal -Registered-Trademark -L* - - Adhesion prevention - Seprafilm-TM- - Sepramesh-TM- - Hylasine -Registered-Trademark *Pending FDA approval SLIDE: A High Value Pipeline - - Bio-orthopedics - Carticel -Registered-Trademark II for cartilage damage - OA5025 for osteoarthritis - Synvisc -Registered-Trademark (other joints) - - Bio-Cardiothoracic - Gene therapy for serious heart disease -- > HIF-1[ALPHA] for angiogenesis -- > BARKct for congestive heart failure - Cell therapy for heart muscle scarring - Biomaterials -- > FocalSeal-L for CV applications -- > CV Sepra - Adhesion Prevention SLIDE: Creating a Powerful New Biotech Company - - High value products, early in their life cycles - - A high value pipeline resting on well-regarded scientific platforms - - Expertise and infrastructure to build a global business - - Critical mass in emerging markets
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