Exhibit 21.1

Listed below are subsidiaries of UnitedHealth Group Incorporated as of December 31, 2014. Those subsidiaries not listed would not, in the aggregate, constitute a “significant subsidiary” of UnitedHealth Group Incorporated, as that term is defined in Rule 1-02(w) of Regulation S-X.

Name of Entity	State of Jurisdiction or Domicile	Doing Business As
310 Canyon Medical, LLC	CA
ACN Group IPA of New York, Inc.	NY
ACN Group of California, Inc.	CA	OptumHealth Physical Health of California
AHJV MSO, Inc.	DE
AHJV, Inc.	DE
All Savers Insurance Company	IN
All Savers Life Insurance Company of California	CA
AmeriChoice Corporation	DE
AmeriChoice Health Services, Inc.	DE
AmeriChoice of Connecticut, Inc.	CT
AmeriChoice of Georgia, Inc.	GA
AmeriChoice of New Jersey, Inc.	NJ	UnitedHealthcare Community Plan
Amico Saúde Ltda.	Brazil
Amil Assistência Médica Internacional S.A.	Brazil
Amil Clinical Research Participações Ltda.	Brazil
AMIL International S.á.r.l.	Luxembourg
Amil Lifesciences Participações Ltda.	Brazil
Angiografia e Hemodinâmica Madre Theodora Ltda.	Brazil
Arizona Physicians IPA, Inc.	AZ	UnitedHealthcare Arizona Physicians IPA UnitedHealthcare Community Plan
ASI Global, LLC	TX
Audex Health Solutions, LLC	DE
Aveta Arizona, Inc.	AZ
Aveta Health Solutions Inc.	DE
Aveta Inc.	DE
Aveta Kansas City, Inc.	KS
Aveta Tennessee, Inc	DE
bConnected Software, Inc.	DE
Behavioral Healthcare Options, Inc.	NV
Bosque Medical Center S.A.	Brazil
Cardio Management, Inc.	DE
Care Improvement Plus Group Management, LLC	MD
Care Improvement Plus of Maryland, Inc.	MD
Care Improvement Plus of Texas Insurance Company	TX	Care Improvement Plan
Care Improvement Plus Practitioners, LLC	MD
Care Improvement Plus South Central Insurance Company	AR
Care Improvement Plus Wisconsin Insurance Company	WI
Catalyst360, LLC	DE
Cemed Care Empresa de Atendimento Clínico Geral Ltda.	Brazil
ChinaGate (Hong Kong) Limited	Hong Kong	OptumInsight
ChinaGate Company Limited	China
Coachella Valley Physicians of PrimeCare, Inc.	CA
Collaborative Care Holdings, LLC	DE
Collaborative Care Services, Inc.	DE
Collaborative Care Solutions, LLC	DE	Next Door Health

Collaborative Realty, LLC	NY
Comfort Care Transportation, LLC	TX
Commonwealth Administrators, LLC	KY
Connextions HCI NM, LLC	NM
Connextions, Inc.	FL	Connextions Connextions Health
DBP Services of New York IPA, Inc.	NY
Dental Benefit Providers of California, Inc.	CA	OptumHealth Dental of California
Dental Benefit Providers of Illinois, Inc.	IL
Dental Benefit Providers, Inc.	DE	DBP Services DBP Services Inc.
Dental Center Serviços Odontológicos Ltda.	Brazil
Distance Learning Network, Inc.	DE	i3CME OptumHealth Education
Duncan Printing Services, LLC	SC
Electronic Network Systems, Inc.	DE
ELG FZE	Dubai
Esho – Empresa de Serviços Hospitalares S.A.	Brazil
Etho – Empresa de Tecnologia Hospitalar Ltda.	Brazil
Evercare Collaborative Solutions, Inc.	DE
Excellion Serviços Biomédicos S.A.	Brazil
Executive Health Resources, Inc.	PA
Family Health Care Services	NV
Family Home Hospice, Inc.	NV
FMG Holdings, LLC	DE
FOR HEALTH OF ARIZONA, INC.	AZ	Care Level Management of Arizona Medical Services INSPRIS of Arizona
For Health, Inc.	DE
Frontier Medex Tanzania Limited	Tanzania
FrontierMEDEX (RMS), Inc.	DE
FrontierMEDEX Canada Holdings Ltd.	Canada
FrontierMEDEX Canada Limited	Canada
FrontierMEDEX Government Services, LLC	DE
FrontierMEDEX Kenya Limited	Kenya
FrontierMEDEX Limited	UK
FrontierMEDEX US, Inc.	DE
FrontierMEDEX, Inc.	MN	UnitedHealthcare Global
Golden Rule Financial Corporation	DE
Golden Rule Insurance Company	IN	UnitedHealthOne
H&W Indemnity (SPC), Ltd.	Caymans
Health Net Insurance of New York, Inc.	NY
Health Net Services (Bermuda) Ltd.	Bermuda
Health Plan of Nevada, Inc.	NV
Health Technology Analysts Pty. Limited	Australia	Innovus OptumInsight
HealthAllies, Inc.	DE	OptumHealth Allies UnitedHealth Allies
Hospice Inspiris Holdings, Inc.	TN
Hospital Alvorada de Taguatinga Ltda.	Brazil
Hospital AMA S.A.	Brazil
Hospital Carlos Chagas S.A.	Brazil

Hospital e Maternidade Saint-Vivant Ltda.	Brazil
Hospital Geral e Maternidade Madre Maria Theodora Ltda.	Brazil
HPP - Medicina Molecular, S.A.	Portugal
HPP Viseu, S.A.	Portugal
Humedica, Inc.	DE
Hygeia Corporation	DE
Hygeia Corporation (Ontario)	Ontario
Imed Star – Serviços de Desempenho Organizacional Ltda.	Brazil
Ingram & Associates, LLC	TN	Ingram & Associates, LLC (Tennessee) Ingram & Associates, (Tennessee) LLC Ingram BPO Services, LLC
INSPIRIS of New York IPA, Inc.	NY	Care Level Management of New York INSPIRIS of New York IPA
INSPIRIS of New York Management, Inc.	NY	INSPIRIS of New York Management
Inspiris of Tennessee, Inc.	TN
INSPIRIS of Texas Physician Group	TX
Inspiris Services Company	TN	Care Level Management of Florida Inspiris of Florida
Inspiris, Inc.	DE
International Psychological Services Pty Limited	Australia	IPS Conferences IPS Worldwide
Lifeprint Accountable Care Organization, LLC	DE
Lifeprint East, Inc.	DE
Lifeprint Health, Inc.	DE	Optum Medical Network
LMN – Laboratório de Medicina Nuclear, Unipessoal, Lda.	Portugal
Logisitics Health, Inc.	WI
Lusíadas A.C.E.	Portugal
Lusíadas, S.A.	Portugal
Lusíadas, SGPS, S.A.	Portugal
Lusíadas-Parcerias Cascais, S.A.	Portugal
MAMSI Insurance Resources, LLC	MD
MAMSI Life and Health Insurance Company	MD	MAMSI LIFE AND HEALTH MLH
Managed Physical Network, Inc.	NY
MD Ops, Inc.	CA
MD-Individual Practice Association, Inc.	MD	M.D. IPA M.D. IPA HEALTH M.D. IPA PREFERRED
MEDEX Insurance Services, Inc.	MD
Medica Health Plans of Florida, Inc.	FL	EZ Care
Medica Healthcare Plans, Inc.	FL
Medical Preparatory School of Allied Health, LLC	TX
Medical Transportation Services, LLC	FL
MedSynergies North Texas, Inc.	TX
MedSynergies, Inc.	DE
MHC Real Estate Holdings, LLC	CA
Midwest Security Life Insurance Company	WI
Monarch Financial Services, LLC	CA
Monarch Management Services, Inc.	DE
Mustang Razorback Holdings, Inc.	DE
NAMM Holdings, Inc.	DE
National Pacific Dental, Inc.	TX

Neighborhood Health Partnership, Inc.	FL	Neighborhood Health Neighborhood Health Partnership NHP
Netwerkes, LLC	TN
Nevada Medical Services LLC	NV	Optum Collaborative Care Services
Nevada Pacific Dental	NV
North American Medical Management - Illinois, Inc.	IL
North American Medical Management California, Inc.	TN
Northern Nevada Health Network, Inc.	NV
OneNet PPO, LLC	MD
Optimum Choice, Inc.	MD	OCI OCI HEALTH PLAN OCI PREFERRED OPTIMUM CHOICE OPTIMUM CHOICE ADVANTAGE OPTIMUM CHOICE HEALTH PLAN OPTIMUM CHOICE PREFERRED
Optum (Spain) S.A.U.	Spain
Optum Bank, Inc.	UT	Exante Bank OptumHealth Bank, Inc.
Optum Biometrics, Inc.	IL	Wellness, Inc. Wellness, Inc., which will do business in California as Illinois Wellness, Inc.
Optum Clinical Services, Inc.	DE	Optum Staffing Services, Inc.
Optum Clinical Solutions, Inc.	DE	Lynx Medical Systems
Optum Clinical Solutions, Ltd.	UK
Optum Global Solutions International B.V.	Netherlands
Optum Government Solutions, Inc.	DE	Integris Integris Inc.
Optum Health & Technology (Australia) Pty Ltd	Australia	PPC Worldwide Holdings Pty Ltd
Optum Health & Technology (India) Private Limited	India
Optum Health & Technology (Singapore) Pte. Ltd.	Singapore
Optum Health & Technology (UK) Limited	UK
Optum Health & Technology (US), LLC	MO
Optum Health & Technology Holdings (US), LLC	MO
Optum Health & Technology Serviços Do Brasil Ltda.	Brazil
Optum Health Services (Canada) Ltd.	Canada	Interlock Employee and Family Assistance
Optum Health Solutions (UK) Limited	UK
Optum Labs Dimensions, Inc.	DE
Optum Labs, Inc.	DE
Optum Life Sciences (Canada) Inc.	Canada
Optum Medical Management Consulting (Shanghai) Co., Ltd.	PRC
Optum Nevada Accountable Care Organization LLC	DE
Optum Palliative and Hospice Care of Pennsylvania, Inc.	TN	Evercare Hospice & Palliative Care
Optum Palliative and Hospice Care of Texas, Inc.	TN	Evercare Hospice & Palliative Care

Optum Palliative and Hospice Care, Inc.	DE	Evercare Hospice Evercare Hospice and Palliative Care Evercare Hospice and Palliative Care of Colorado Springs Evercare Hospice and Palliative Care of Denver Evercare Palliative Care Evercare Palliative Services Evercare Palliative Services of Atlanta Evercare Palliative Services of Cincinnati Evercare Palliative Services of Cleveland Evercare Palliative Services of Colorado Springs Evercare Palliative Services Denver Evercare Palliative Services of Dover Evercare Palliative Services of Eugene Evercare Palliative Services of Houston Evercare Palliative Services of Phoenix Evercare Palliative Services of Portland Evercare Palliative Services of Salem Evercare Palliative Services of Tucson Evercare Palliative Services of Vienna Hospice Care Suites
Optum Public Sector Solutions, Inc.	DE	Ingenix Public Sector Solutions Ingenix Public Sector Solutions, Inc.
Optum Rocket, Inc.	DE
Optum Services, Inc.	DE
Optum Solutions UK Holdings Limited	UK
Optum Technology, Inc.	DE
Optum UK Solutions Group Limited	UK
Optum, Inc.	DE
Optum360 Services, Inc.	DE
Optum360, LLC	DE
OptumHealth Care Solutions, Inc.	MN	OptumHealth Care Solutions
OptumHealth Financial Services, Inc.	DE
OptumHealth Holdings, LLC	DE
OptumHealth International B.V.	Netherlands
OptumInsight Holdings, LLC	DE
OptumInsight Life Sciences, Inc.	DE	CanReg Innovus QualityMetric QualityMetric Incorporated
OptumInsight, Inc.	DE	Ingenix Ingenix, Inc. Optum
OptumRx Holdings, LLC	DE
OptumRx NY IPA, Inc.	NY
OptumRx, Inc.	CA	FirstLine Medical hi HealthInnovations OptumRx Prescription Solutions by OptumRx Prescription Solutions PRESCRIPTION SOLUTIONS
OrthoNet Holdings, Inc.	DE
OrthoNet LLC	NY
OrthoNet New York IPA, Inc.	NY
OrthoNet of the Mid-Atlantic, Inc.	DE
OrthoNet of the South, Inc.	DE
OrthoNet Services, Inc.	DE

OrthoNet West, Inc.	DE
Ovations, Inc.	DE
Oxford Benefit Management, Inc.	CT
Oxford Health Insurance, Inc.	NY
Oxford Health Plans (CT), Inc.	CT
Oxford Health Plans (NJ), Inc.	NJ
Oxford Health Plans (NY), Inc.	NY
Oxford Health Plans LLC	DE	Oxford Agency - Oxford Health Plans, Inc.
PacifiCare Life and Health Insurance Company	IN	UnitedHealthOne
PacifiCare Life Assurance Company	CO	UnitedHealthOne
PacifiCare of Arizona, Inc.	AZ	PacifiCare Secure Horizons
PacifiCare of Colorado, Inc.	CO	Comprecare, Inc. Secure Horizons
PacifiCare of Nevada, Inc.	NV	PacifiCare Secure Horizons
Payment Resolution Services, LLC	TN	AIM Healthcare Services AIM Healthcare Services, LLC AIM Services
PCCCV, Inc.	CA
PHC Subsidiary Holdings, LLC	TX
PHYS Holding Corp.	DE
PhyServe Holdings, Inc.	DE
Physician Care Partners, Inc.	IL
Physicians Health Choice of Texas, LLC	TX	Physicians Health Choice
Physicians Health Plan of Maryland, Inc.	MD
Plus One Health Management Puerto Rico, Inc.	PR
Plus One Holdings, Inc.	DE
Polar II Fundo de Investimento em Participações	Brazil
ppoONE, Inc.	DE
Preferred Care Partners Holding, Corp.	FL	UnitedHealthcare
Preferred Care Partners Medical Group, Inc.	FL	Preferred Care Partners Medical Group of Hialeah Preferred Care Partners Medical Group of Little Havana Preferred Care Partners Medical Group of North Shore Preferred Care Partners Medical Group of Red Road Preferred Care Partners Medical Group of West Hialeah Preferred Care Partners Medical Group of Westchester
Preferred Care Partners, Inc.	FL	CareFlorida Preferred Care Partners
Premier Choice ACO, Inc.	CA
Prime Health, Inc.	NV	Med One Works
PrimeCare Medical Network, Inc.	CA
PrimeCare of Citrus Valley, Inc.	CA
PrimeCare of Corona, Inc.	CA
PrimeCare of Hemet Valley, Inc.	CA
PrimeCare of Inland Valley, Inc.	CA
PrimeCare of Moreno Valley, Inc.	CA
PrimeCare of Redlands, Inc.	CA
PrimeCare of Riverside, Inc.	CA

PrimeCare of San Bernardino, Inc.	CA
PrimeCare of Sun City, Inc.	CA
PrimeCare of Temecula, Inc.	CA
ProHEALTH Fitness of Lake Success, LLC	NY
ProHealth Medical Management, LLC	DE
Promarket Propaganda e Marketing Ltda.	Brazil
QSSI Technologies India Private Limited	India
Quality Software Services, Inc.	MD	Optum Optum, Inc. Q.S.S., Inc. QSSI
R&H Family Fitness Unlimited LLC	TX	Elvira Cisneros Community Center by WellMed Family Fitness Limited
Rally Health, Inc.	DE
ScriptSwitch Limited	UK
Seisa Serviços Integrados de Saúde Ltda.	Brazil
Senior Care Partners, Inc.	IL
Sierra Health and Life Insurance Company, Inc.	NV
Sierra Health Services, Inc.	NV	Sierra Military Health Services, LLC
Sierra Health-Care Options, Inc.	NV
Sierra Home Medical Products, Inc.	NV	THC of Nevada TCH of Nevada Pharmacy
Sierra Nevada Administrators, Inc.	NV
Southwest Medical Associates, Inc.	NV	SMA Convenient Care SMA Lifestyle Center Southwest Hospitalist Services Group
Southwest Michigan Health Network Inc.	MI
Specialty Benefits, LLC	DE	EyeFit EyeFit Vision Center EyeFit Vision Centers
Spectera of New York, IPA, Inc.	NY
Spectera, Inc.	MD	CARE Programs, a division of Spectera, Inc. Health Benefit Services, Inc. Spectera United Optical
Spotlite, Inc.	DE
The Lewin Group, Inc.	NC	Lewin
Three Rivers Holdings, Inc.	DE
Travel Express Incorporated	MD
U.S. Behavioral Health Plan, California	CA	Life Strategies OptumHealth Behavioral Solutions of California
UHC International Services, Inc.	DE
UHC of California	CA	PacifiCare PacifiCare of California Secure Horizons UnitedHealthcare of California
UHG Brasil Participações S.A.	Brazil
UHIC Holdings, Inc.	DE
Ultima Rx, LLC	FL
UMR, Inc.	DE	Avidyn Health Fiserv Health - Kansas Fiserv Health - Wausau Benefits UMR UMR, Inc.

Unimerica Insurance Company	WI	Unimerica Life Insurance Company
Unimerica Life Insurance Company of New York	NY
Unison Administrative Services, LLC	PA
Unison Health Plan of Delaware, Inc.	DE	UnitedHealthcare Community Plan
Unison Health Plan of the Capital Area, Inc.	DC	UnitedHealthcare Community Plan
United Behavioral Health	CA	Life Strategies OptumHealth Behavioral Solutions Plan 21, INCORPORATED Plan 21, Incorporated United Behavioral Health (Inc.) United Behavioral Health, Inc.
United Behavioral Health of New York, I.P.A., Inc.	NY
United Health Foundation	MN	United Health Hospice Foundation
United HealthCare Services, Inc.	MN	AmeriChoice Center for Health Care Policy and Evaluation Charter HealthCare, Inc. Employee Performance Design Evercare Health Professionals Review Healthmarc HealthPro Institute for Human Resources Optum UHC Management Company UHC Management Company, Inc. Unimerica Workplace Benefits United HealthCare Corporation United HealthCare Management Company, Inc. United HealthCare Management Services United HealthCare Services of Minnesota United HealthCare Services of Minnesota, Inc. United Resource Networks United Resource Networks, Inc. UnitedHealth Products UnitedHealthcare Medicare Store
United Resource Networks IPA of New York, Inc.	NY
UnitedHealth Advisors, LLC	ME	UnitedHealthcare
UnitedHealth Group Global Healthcare Services Limited	Ireland
UnitedHealth Group Global Services, Inc.	Philippines
UnitedHealth Group Incorporated	MN	UnitedHealth Group
UnitedHealth Group Information Services Private Limited	India
UnitedHealth Group International GP	Caymans
UnitedHealth Group International L.P.	Caymans
UnitedHealth International, Inc.	DE
UnitedHealth Military & Veterans Services, LLC	DE
UnitedHealth UK Limited	UK
UnitedHealthcare Benefits of Texas, Inc.	TX	PacifiCare Secure Horizons
UnitedHealthcare Community Plan of California, Inc.	CA
UnitedHealthcare Community Plan of Ohio, Inc.	OH	Unison Unison ABD Plus Unison Advantage Unison Health Plan Unison Kids
UnitedHealthcare Community Plan of Texas, L.L.C.	TX	United Healthcare - Texas UnitedHealthcare Community Plan
UnitedHealthcare Community Plan, Inc.	MI

UnitedHealthcare Consulting & Assistance Service (Beijing) Co., Ltd.	China
UnitedHealthcare Europe S.á.r.l.	Luxembourg
UnitedHealthcare India Private Limited	India
UnitedHealthcare Insurance Company	CT	UnitedHealthOne
UnitedHealthcare Insurance Company of Illinois	IL
UnitedHealthcare Insurance Company of New York	NY
UnitedHealthcare Insurance Company of the River Valley	IL
UnitedHealthcare Integrated Services, Inc.	AZ	Evercare Select UnitedHealthcare Community Plan
UnitedHealthcare International Asia, LLC	DE
UnitedHealthcare International I B.V.	Netherlands
UnitedHealthcare International I S.á.r.l.	Luxembourg
UnitedHealthcare International II B.V.	Netherlands
UnitedHealthcare International II S.á.r.l.	Luxembourg
UnitedHealthcare International III S.á.r.l.	Luxembourg
UnitedHealthcare International IV S.á.r.l.	Luxembourg
UnitedHealthcare Life Insurance Company	WI	UnitedHealthOne
UnitedHealthcare of Alabama, Inc.	AL
UnitedHealthcare of Arizona, Inc.	AZ
UnitedHealthcare of Arkansas, Inc.	AR	Complete Health
UnitedHealthcare of Colorado, Inc.	CO	MetraHealth Care Plan
UnitedHealthcare of Florida, Inc.	FL	AMERICHOICE EVERCARE AT HOME OPTUMHEALTH OVATIONS
UnitedHealthcare of Georgia, Inc.	GA	United HealthCare of Georgia
UnitedHealthcare of Illinois, Inc.	IL
UnitedHealthcare of Kentucky, Ltd.	KY	United Healthcare of Kentucky, L.P.
UnitedHealthcare of Louisiana, Inc.	LA	UnitedHealthcare Community Plan
UnitedHealthcare of Mississippi, Inc.	MS
UnitedHealthcare of New England, Inc.	RI
UnitedHealthcare of New Mexico, Inc.	NM
UnitedHealthcare of New York, Inc.	NY	UnitedHealthcare Community Plan
UnitedHealthcare of North Carolina, Inc.	NC
UnitedHealthcare of Ohio, Inc.	OH
UnitedHealthcare of Oklahoma, Inc.	OK	PacifiCare PacifiCare Health Options PacifiCare of Oklahoma Secure Horizons
UnitedHealthcare of Oregon, Inc.	OR	Secure Horizons
UnitedHealthcare of Pennsylvania, Inc.	PA
UnitedHealthcare of Texas, Inc.	TX
UnitedHealthcare of the Mid-Atlantic, Inc.	MD
UnitedHealthcare of the Midlands, Inc.	NE
UnitedHealthcare of the Midwest, Inc.	MO
UnitedHealthcare of Utah, Inc.	UT	UnitedHealthcare of Idaho, Inc.
UnitedHealthcare of Washington, Inc.	WA	PacifiCare Secure Horizons UnitedHealthcare Community Plan
UnitedHealthcare of Wisconsin, Inc.	WI	UnitedHealthcare of Wisconsin - Personal Care Plus
UnitedHealthcare Plan of the River Valley, Inc.	IL

UnitedHealthcare Service LLC	DE
UnitedHealthcare Services Company of the River Valley, Inc.	DE
UnitedHealthcare Specialty Benefits, LLC	ME	UnitedHealthcare Specialty Benefits
UnitedHealthcare, Inc.	DE
UnitedHealthOne Agency, Inc.	IN	UnitedOne Insurance Agency
Valley Physicians Network, Inc.	CA
WellMed Medical Management of Florida, Inc.	FL	WellMed at 9th Ave. North WellMed at Bartow WellMed at Downtown Clearwater WellMed at Fort Pierce WellMed at Lake Copeland WellMed at Longwood WellMed at Oak Commons WellMed at Port St. Lucie - East WellMed at Port St. Lucie - West WellMed at Rosemount WellMed at Sanford WellMed at SE Lakeland WellMed at Sebastian WellMed at South Stuart
WellMed Medical Management, Inc.	TX	DataRaps, Inc. HealthRight / ITC Rosa Verde Silver Life Fitness
WESTMED Practice Partners LLC	DE
XLHealth Corporation	MD
XLHealth Corporation India Private Limited	India
Your Health Options Insurance Services, Inc.	CA
Your Partner in Health Services, Inc.	IL