Share-based Compensation (Tables)

9 Months Ended

Sep. 30, 2014

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

The per-share weighted-average fair value of stock options granted during the three and nine months ended September 30, 2014 was $0.45 and $0.72, respectively, and $0.26 and $0.55 for the three and nine months ended September 30, 2013, respectively, on the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumptions:

Period	Expected Dividend Yield	Risk-Free Interest Rate	Expected Option Life	Expected Volatility Factor
Three Months Ended September 30, 2014	—	1.63%	5.1 years	101.7%
Nine Months Ended September 30, 2014	—	1.62%	5.1 years	104.6%
Three Months Ended September 30, 2013	—	1.40%	5.1 years	99.8%
Nine Months Ended September 30, 2013	—	0.97%	5.1 years	99.8%

The risk free interest rate reflects treasury yields rates over a term that approximates the expected option life. The expected option life is calculated based on historical lives of all options issued under the Plans.  The expected volatility factor is determined by measuring the actual stock price volatility over a term equal to the expected useful life of the options granted.

Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan

The Company has recognized share-based compensation expense of approximately $39 thousand and $88 thousand for the nine months ended September 30, 2014 and 2013, respectively. The total non-cash, share-based compensation expense included in the unaudited condensed consolidated statements of operations for the periods presented is included in the following expense categories:

	Three Months Ended September 30,				Nine Months Ended September 30,
(in thousands)	2014		2013		2014		2013
Cost of contract research, services	$	—	$	1	$	—	$	11
Cost of goods sold	—		—		—		7
Administrative and selling	8		10		39		70
Total share-based compensation	$	8	$	11	$	39	$	88

No share-based compensation expense was capitalized during the nine months ended September 30, 2014 and 2013. Compensation expense related to stock options to be charged in future periods amounts to zero at September 30, 2014.

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value

A summary of options outstanding under the Plans as of September 30, 2014 and changes during the nine-month period ended September 30, 2014 is as follows:

	Number of Shares		Weighted-Average Exercise Price		Average Remaining Contractual Life (Years)	Aggregate Intrinsic Value (in thousands)
Options Outstanding at December 31, 2013	527,246		$	5.88
Granted	36,000		$	0.72
Exercised	—		$	—
Cancelled/expired	(16,248	)	$	5.57
Options outstanding at September 30, 2014	546,998		$	5.55	4.86	$	1
Options vested and exercisable at September 30, 2014	546,998		$	5.55	4.86	$	1
Option vested and expected to vest at September 30, 2014	546,998		$	5.55	4.86	$	—
Options available for future grant at September 30, 2014	450,259