Stock based Compensation and Stock Option Plan (Tables)

9 Months Ended

Sep. 30, 2012

Stock based Compensation and Stock Option Plan [Abstract]

Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block]

The Company has recognized stock-based compensation expense of approximately $48 thousand and $78 thousand for the three months ended September 30, 2012 and 2011, respectively. The Company has recognized stock-based compensation expense of approximately $169 thousand and $284 thousand for the nine months ended September 30, 2012 and 2011, respectively. The total non-cash, stock-based compensation expense included in the unaudited condensed consolidated statements of operations for the periods presented is included in the following expense categories:

	Three Months Ended September 30,				Nine Months Ended September 30,
(in thousands)	2012		2011		2012		2011
Cost of contract research, services	$	6	$	5	$	16	$	16
Cost of goods sold	6		17		31		59
Administrative and selling	36		56		122		209
Total stock-based compensation	$	48	$	78	$	169	$	284

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block]

A summary of options outstanding under the Plans as of September 30, 2012 and changes during the nine month period ended September 30, 2012 is as follows:

	Number of Shares		Weighted-Average Exercise Price		Average Remaining Contractual Life (Years)	Aggregate Intrinsic Value
Options Outstanding at December 31, 2011	793,107		$	6.40
Granted	30,000		$	0.83
Exercised	—		$	—
Cancelled/expired	(183,661	)	$	7.25
Options Outstanding at September 30, 2012	639,446		$	6.28	6.02	$	—
Options Exercisable at September 30, 2012	568,196		$	6.44	5.85	$	—
Option vested and expected to vest at September 30, 2012	634,909		$	6.45	5.84	$	—

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

The per-share weighted-average fair value of stock options granted during the three and nine months ended September 30, 2012 was $0.55 and $0.83, respectively, and $1.29 and $2.20 for the three and nine months ended September 30, 2011, respectively, on the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumptions:

Year	Expected Dividend Yield	Risk-Free Interest Rate	Expected Option Life	Expected Volatility Factor
2012	—	0.62%	5.1 years	92.1%
2011	—	1.54%	5.1 years	77.9%