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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
 
                                    FORM 15
 
 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(G) OF
THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER
          SECTIONS 13 AND 15(D) OF THE SECURITIES EXCHANGE ACT OF 1934
 
                         COMMISSION FILE NUMBER 0-14339
 
                               AMGEN BOULDER INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
 
                       (FORMERLY KNOWN AS SYNERGEN, INC.)
 
                                C/O AMGEN, INC.
                                  AMGEN CENTER
                             1840 DEHAVILLAND DRIVE
                          THOUSAND OAKS, CA 91320-1789
                                 (805) 447-1000
  (ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE, OF
                   REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)
 
                         COMMON STOCK $.01 PAR VALUE;
       RIGHTS TO PURCHASE SERIES A JUNIOR PARTICIPATING PREFERRED STOCK
            (TITLE OF EACH CLASS OF SECURITIES COVERED BY THIS FORM)
 
                                      NONE
(TITLE OF ALL OTHER CLASSES OF SECURITIES FOR WHICH A DUTY TO FILE REPORTS UNDER
                        SECTION 13(A) OR 15(D) REMAINS)
 
     Please place an X in the box(es) to designate the appropriate rule
provision(s) relied upon to terminate or suspend the duty to file reports:
 
                                                         
Rule 12g-4(a)(1)(i)           /X/    Rule 12h-3(b)(1)(ii)          / /
Rule 12g-4(a)(1)(ii)          / /    Rule 12h-3(b)(2)(i)           / /
Rule 12g-4(a)(2)(i)           / /    Rule 12h-3(b)(2)(ii)          / /
Rule 12g-4(a)(2)(ii)          / /
Rule 12h-3(b)(1)(i)           / /    Rule 15d-6                    / /


 
Approximate number of holders of record as of the certification or notice date:
 
    1 HOLDER OF COMMON STOCK, $.01 PAR VALUE; 1 HOLDER OF RIGHTS TO PURCHASE
                 SERIES A JUNIOR PARTICIPATING PREFERRED STOCK
 
     Pursuant to the requirements of the Securities Exchange Act of 1934 AMGEN
BOULDER INC. has caused this certification/notice to be signed on its behalf by
the undersigned duly authorized person.
 
                                    
DATE:    March 28, 1995                BY:    /s/  Thomas E. Workman, Jr.
     ----------------------               -----------------------------------
                                             Vice President, Secretary and
                                                    General Counsel


 
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