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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2020
Stock-Based Compensation Expense The following table presents stock-based compensation expense in the Company’s consolidated statements of comprehensive income:
    
For the Years Ended December 31,
 
    
2020
    
2019
    
2018
 
    
(Amounts in thousands)
 
Cost of product revenue
   $ 1,929      $ 1,368      $ 1,019  
Research and development
     1,534        1,373        917  
Selling, general and administrative
     13,544        10,106        8,256  
    
 
 
    
 
 
    
 
 
 
Total stock-based compensation
   $ 17,007      $ 12,847      $ 10,192  
    
 
 
    
 
 
    
 
 
 
Estimated Weighted Average Assumptions
The fair value of share-based awards granted during the years ended December 31, 2020, 2019 and 2018 were calculated using the following estimated assumptions:
 
    
For the Years Ended December 31,
    
2020
  
2019
  
2018
Expected term (in years)
  
5.5-6.5
  
5.5-6.5
  
5.5-7.5
Expected volatility (range)
   45.14 – 50.87%    45.14 – 50.87%    45.14 – 50.87%
Risk-free interest rate
   0.34 – 1.15%    1.55 – 2.56%    2.63 – 2.96%
Expected dividend yield
   0%    0%    0%
Summary of Option Activity
Information regarding option activity for the year ended December 31, 2020 under the Plans is summarized below:
 
    
Shares
    
Weighted

average

exercise

price
    
Weighted-

Average

Remaining

Contractual

Term

(in Years)
    
Aggregate

Intrinsic

Value

(in Thousands)
 
Options outstanding at December 31, 2019
     957,559      $ 30.81                    
Granted
     79,698      $ 115.81                    
Exercised
     (340,546    $ 23.95                    
Forfeited/expired/cancelled
     —        $ —                      
    
 
 
                            
Options outstanding at December 31, 2020
     696,711      $ 43.88        6.90      $ 102,958  
    
 
 
                            
Options exercisable at December 31, 2020
     311,988      $ 31.75        5.91      $ 49,879  
    
 
 
                            
Vested and expected to vest at December 31, 2020
(1)
     667,220                 6.86      $ 99,096  
    
 
 
                            
 
(1)
Represents the number of vested options as of December 31, 2020 plus the number of unvested options expected to vest as of December 31, 2020 based on the unvested outstanding options at December 31, 2020 adjusted for estimated forfeiture rates of 8% for awards granted to
non-executive
level employees and 3% for awards granted to executive level employees.
Summary of Restricted Stock Unit Activity
The fair value of stock units is calculated using the closing price of the Company’s common stock on the date of grant. Information regarding stock unit activity, which includes activity for restricted stock units and performance stock units, for the year ended December 31, 2020 under the Plans is summarized below:
 
    
Shares
    
Weighted-

Average

Remaining

Contractual

Term

(in Years)
    
Aggregate

Intrinsic

Value

(in Thousands)
 
Unvested at December 31, 2019
     734,984                    
Awarded
     207,788                    
Vested
     (244,648                  
Forfeited/expired/cancelled
     (32,584                  
    
 
 
                   
Unvested at December 31, 2020
     665,540        3.32      $ 127,904  
    
 
 
                   
Vested and expected to vest at December 31, 2020
(1)
     650,047        3.01      $ 124,568  
    
 
 
                   
 
(1)
Represents the number of vested stock units as of December 31, 2020 plus the number of unvested stock units expected to vest as of December 31, 2020 based on the unvested outstanding stock units at December 31, 2020 adjusted for estimated forfeiture rates of 8% for awards granted to
non-executive
level employees and 3% for awards granted to executive level employees.